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| Product | Description | |
|---|---|---|
| Sepantronium | Sepantronium, also known as YM-155, is a small-molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and tumor cell apoptosis. Survivin, a member of the inhibitor of apoptosis (IAP) gene family, is expressed during embryonal development and is absent in most normal, terminally differentiated tissues; upregulated in a variety of human cancers, its expression in tumors is associated with a more aggressive phenotype, shorter survival times, and a decreased response to chemotherapy. Uses: For research used only. Synonyms: YM155; YM 155; YM-155; Sepantronium bromide. Grades: >98%. CAS No. 781661-94-7. Molecular formula: C20H19BrN4O3. Mole weight: 443.29386. |  |
| Sepantronium bromide | Sepantronium bromide (YM-155) is a survivin inhibitor with an IC 50 of 0.54 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM-155. CAS No. 781661-94-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10194. |  |
| YM155 | YM155. Group: Biochemicals. Alternative Names: 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium Bromide; Sepantronium bromide; YM 155. Grades: Highly Purified. CAS No. 781661-94-7. Pack Sizes: 10mg. Molecular Formula: C20H19BrN4O3, Molecular Weight: 443.29. US Biological Life Sciences. |  Worldwide |
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