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| Product | Description | |
|---|---|---|
| sepiapterin deaminase | Also acts on isosepiapterin, but more slowly. Group: Enzymes. Enzyme Commission Number: EC 3.5.4.24. CAS No. 62213-22-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4551; sepiapterin deaminase; EC 3.5.4.24; 62213-22-3. Cat No: EXWM-4551. |  |
| sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) | This enzyme catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP. The enzyme, which is found in higher animals and some fungi and bacteria, produces the erythro form of tetrahydrobiopterin. cf. EC 1.1.1.325, sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming). Group: Enzymes. Synonyms: SR. Enzyme Commission Number: EC 1.1.1.153. CAS No. 9059-48-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0058; sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming); EC 1.1.1.153; 9059-48-7; SR. Cat No: EXWM-0058. | |
| sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) | This enzyme, isolated from the bacterium Chlorobium tepidum, catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP. cf. EC 1.1.1.153, sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming). Group: Enzymes. Enzyme Commission Number: EC 1.1.1.325. CAS No. 9059-48-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0238; sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming); EC 1.1.1.325; 9059-48-7. Cat No: EXWM-0238. | |
| L-Sepiapterin | L-Sepiapterin is a key intermediate in the pterin salvage pathway of tetrahydrobiopterin biosynthesis. L-Sepiapterin is an inhibitor of GCH-I. Applications: An intermediate in the pterin salvage pathway. Group: Coenzymes. Synonyms: 2-Amino-6-(S)-lactoyl-7,8-dihydro-4(3H)-pteridinone. CAS No. 17094-01-8. Purity: ≥98%. Mole weight: 237.21. Appearance: Powder. Form: Solid. 2-Amino-6-(S)-lactoyl-7,8-dihydro-4(3H)-pteridinone; L-Sepiapterin; 17094-01-8. Cat No: COEC-065. | |
| 4(3H)-Pteridinone,2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]- | 4(3H)-Pteridinone,2-amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-. Uses: Designed for use in research and industrial production. Appearance: Solid. CAS No. 17094-01-8. Molecular formula: C9H11N5O3. Mole weight: 237.22. Purity: 0.98. Product ID: ACM17094018. Alfa Chemistry ISO 9001:2015 Certified. Categories: sepiapterin. |  |
| 6-carboxytetrahydropterin synthase | Binds Zn2+. Isolated from the bacteria Bacillus subtilis and Escherichia coli. The reaction is part of the biosynthesis pathway of queuosine.The enzyme from Escherichia coli can also convert 6-pyruvoyl-5,6,7,8-tetrahydropterin and sepiapterin to 6-carboxy-5,6,7,8-tetrahydropterin. Group: Enzymes. Synonyms: CPH4 synthase; queD (gene name); ToyB; ykvK (gene name). Enzyme Commission Number: EC 4.1.2.50. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4887; 6-carboxytetrahydropterin synthase; EC 4.1.2.50; CPH4 synthase; queD (gene name); ToyB; ykvK (gene name). Cat No: EXWM-4887. | |
| 6-pyruvoyltetrahydropterin 2'-reductase | Not identical with EC 1.1.1.153 sepiapterin reductase. Group: Enzymes. Synonyms: 6-pyruvoyltetrahydropterin reductase; 6PPH4(2'-oxo) reductase; 6-pyruvoyl tetrahydropterin (2'-oxo)reductase; 6-pyruvoyl-tetrahydropterin 2'-reductase; pyruvoyl-tetrahydropterin reductase. Enzyme Commission Number: EC 1.1.1.220. CAS No. 97089-79-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0126; 6-pyruvoyltetrahydropterin 2'-reductase; EC 1.1.1.220; 97089-79-7; 6-pyruvoyltetrahydropterin reductase; 6PPH4(2'-oxo) reductase; 6-pyruvoyl tetrahydropterin (2'-oxo)reductase; 6-pyruvoyl-tetrahydropterin 2'-reductase; pyruvoyl-tetrahydropterin reductase. Cat No: EXWM-0126. | |
| 6-pyruvoyltetrahydropterin synthase | Catalyses triphosphate elimination and an intramolecular redox reaction in the presence of Mg2+. It has been identified in human liver. This enzyme is involved in the de novo synthesis of tetrahydrobiopterin from GTP, with the other enzymes involved being EC 1.1.1.153 (sepiapterin reductase) and EC 3.5.4.16 (GTP cyclohydrolase I). Group: Enzymes. Synonyms: 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase; 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming). Enzyme Commission Number: EC 4.2.3.12. CAS No. 97089-82-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5132; 6-pyruvoyltetrahydropterin synthase; EC 4.2.3.12; 97089-82-2; 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase; 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming). Cat No: EXWM-5132. | |
| GTP cyclohydrolase I | The reaction involves hydrolysis of two C-N bonds and isomerization of the pentose unit; the recyclization may be non-enzymic. This enzyme is involved in the de novo synthesis of tetrahydrobiopterin from GTP, with the other enzymes involved being EC 1.1.1.153 (sepiapterin reductase) and EC 4.2.3.12 (6-pyruvoyltetrahydropterin synthase). Group: Enzymes. Synonyms: GTP cyclohydrolase; guanosine triphosphate cyclohydrolase; guanosine triphosphate 8-deformylase; dihydroneopterin triphosphate synthase; GTP 8-formylhydrolase. Enzyme Commission Number: EC 3.5.4.16. CAS No. 37289-19-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4542; GTP cyclohydrolase I; EC 3.5.4.16; 37289-19-3; GTP cyclohydrolase; guanosine triphosphate cyclohydrolase; guanosine triphosphate 8-deformylase; dihydroneopterin triphosphate synthase; GTP 8-formylhydrolase. Cat No: EXWM-4542. | |
| Homovanillic acid | Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. Uses: Scientific research. Group: Natural products. Alternative Names: Vanilacetic acid. CAS No. 306-08-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-N0384. |  |
| Homovanillic acid (Standard) | Homovanillic acid (Standard) is the analytical standard of Homovanillic acid. This product is intended for research and analytical applications. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. Uses: Scientific research. Group: Natural products. Alternative Names: Vanilacetic acid (Standard). CAS No. 306-08-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0384R. | |
| SPRi 3 | SPRi 3 is a potent inhibitor of sepiapterin reductase (SPR) with IC50 value of 53-74 nM for human SPR. It inhibits BH4 synthesis pathway and attenuates proliferation in naive CD4+ T cells. Synonyms: N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide. Grades: ≥98% by HPLC. CAS No. 1292285-54-1. Molecular formula: C14H18N2O3. Mole weight: 262.3. |  |
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