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| Product | Description | |
|---|---|---|
| SH-5 | SH-5 is a potent and selective Src kinase inhibitor widely used in biomedical research on multiple diseases, including cancer, osteoporosis and cardiovascular disorders. Synonyms: SH-5, SH 5; SH5; PIA-5; PIA5; PIA 5; L-chiro-Inositol, 1-deoxy-6-O-methyl-, 5-[(2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]. Akt inhibitor II. Grades: 98%. CAS No. 701976-54-7. Molecular formula: C29H59O10P. Mole weight: 598.75. |  |
| SH-5 (D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate) | A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt. Group: Biochemicals. Alternative Names: D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| SH5-07 | SH5-07 is a robust hydroxamic acid-based STAT3 inhibitor with an IC50 of 3.9±0.6 μM in in vitro assay, which induce antitumor cell effects in vitro and antitumor response in vivo against human glioma and breast cancer models. It induces antitumor cell effects against malignant cells harboring constitutively-active Stat3. Synonyms: SH5 07; SH507; SH5-07; 4-[ (4-cyclohexylphenyl) methyl-[2-[methyl- (2, 3, 4, 5, 6-pentafluorophenyl) sulfonylamino]acetyl]amino]-N-hydroxybenzamide; SH-5-07. Grades: >98%. CAS No. 1456632-41-9. Molecular formula: C29H28F5N3O5S. Mole weight: 625.61. | |
| Shikonin | Shikonin belongs naphthoquinone isolated from Arnebia sp. It is used as an anti-inflammatory treatment in traditional chinese medicine (TCM). It inhibits chemokine receptor function and suppresses HIV-1. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: (±)-Alkannin; (±)-Shikalkin; (±)-Shikonin; (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone; 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-. Grades: >98%. CAS No. 54952-43-1. Molecular formula: C16H16O5. Mole weight: 288.29. | |
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