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Antigen which supports E-, L-, and P-selectin-dependent adhesion. Synonyms: S Lea; Sialyl Lewisa; 3-Sialyl Lewis; 3'-Sialyl Lewis A; a-NeuNAc-(2>3)-b-D-Gal-(1>3)-(a-L-Fuc-[1>4])-D-GlcNAc; 6-Deoxyhexopyranosyl-(1->4)-[3,5-dideoxy-5-[(1-hydroxyethylidene)amino]non-2-ulopyranonosyl-(2->3)hexopyranosyl-(1->3)]-2-deoxy-2-[(1-hydroxyethylidene)amino]hexose; O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->3)-O-[6-deoxy-alpha-L-galactopyranosyl-(1->4)]-2-(acetylamino)-2-deoxy-D-Glucose. Grades: 95%. CAS No. 92448-22-1. Molecular formula: C31H52N2O23. Mole weight: 820.74.
Sialyl Lewis A pentaose
Sialyl Lewis A pentaose is an intriguing biomedical compound, aiding in studying diverse ailments such as metastatic cancer. Synonyms: Neu5Ac-a-2-3-Gal-b-1-3(Fuc-a-1-4)GlcNAc-b-1-3-Gal. Molecular formula: C37H62N2O28. Mole weight: 982.90.
Sialyl lewis a,sodium salt
Sialyl lewis a,sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Sialyl Lewis a, Sialyl Lea tri, Sialyl-Lewis a, SLea, 3-Sialyl Lewis A, 3-SLea, CID643993, a-NeuNAc-(2>3)-b-D-Gal-(1>3)-(a-L-Fuc-[1>4])-D-GlcNAc, 92448-22-1, D-Glucose, O-(N-acetyl-a-neuraminosyl)-(2>3)-O-b-D-galactopyranosyl-(1>3)-O-[6-deoxy-a-L-galactopyranosyl-(1>4)]-2-(acetylamino)-2-deoxy- (9CI), D-glucose, O-5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranonosyl-(2->3)-O-beta-D-galactopyranosyl-(1->3)-O-[6-deoxy-alpha-L-galactopyranosyl-(1->4)]-2-(acetylamino)-2-deoxy-. Product Category: Heterocyclic Organic Compound. CAS No. 92448-22-1. Molecular formula: C31H52N2O23. Mole weight: 820.74. Purity: 0.96. IUPACName: (2S,4S,5R,6R)-5-acetamido-2-[(2R,3R,4S,5S,6R)-2-[(2R,3R,4R,5R)-2-acetamido-5,6-dihydroxy-1-oxo-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropy. Canonical SMILES: CC1C(C(C(C(O1)OC(C(CO)O)C(C(C=O)NC(=O)C)OC2C(C(C(C(O2)CO)O)OC3(CC(C(C(O3)C(C(CO)O)O)NC(=O)C)O)C(=O)O)O)O)O)O. Density: 1.66g/cm³. Product ID: ACM92448221. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3'-Sialyl-Lewis-a tetrasaccharide.
3-Sialyl-Lewisa
E-selectin ligand, implicated in colon cancer cell adhesion. CAS No. 91847-18-6. Product ID: 3-00443. Molecular formula: C31H52N2O23. Mole weight: 820.74. Reference: Am. J. Pathol., 144, 592, 1994; Science, 258, 9283, 1992. Categories: 3-Sialyl-Lewis a.
3-Sialyl Lewis A-PAA-biotin
3-Sialyl Lewis A-PAA-biotin is a biomedical product acting as a targeted drug delivery system, facilitating the specific binding and delivery of agents to cells expressing selectins, particularly in the research of cancers and inflammatory disorders. Molecular formula: C50H84N6O26S. Mole weight: 1217.29.
3'-Sialyl Lewis A-PAA-biotin
3'-Sialyl Lewis A-PAA-biotin is a biomedical compound assuming a pivotal role in the precise identification and comprehensive examination of specific receptor interactions, particularly those associated with selectin-mediated adhesion. This cutting-edge compound significantly contributes to the comprehensive comprehension and development of therapeutics targeting diseases encompassing cancer, inflammation is and autoimmune disorders. Grades: 95%. Molecular formula: C50H84N6O26S. Mole weight: 1217.29.
3-Sialyl Lewis A-sp-biotin
3-Sialyl Lewis A-sp-biotin is an absolute game-changer in the realm of tumor and cancer research. This revolutionary therapeutic compound, exhibiting an unparallelled affinity for selectin proteins, tirelessly works towards facilitating cell adhesion while effectively inhibiting metastasis. Synonyms: Neu5Ac-a-2-3-Gal-b-1-3(Fuc-a-1-4)GlcNAc-O(CH2)3NHCO(CH2)5NH-biotin. CAS No. 870892-98-1. Molecular formula: C50H84N6O26S. Mole weight: 1217.29.
3-Sialyl-Lewisx
prevents ischemia reperfusion lung injury. CAS No. 98603-84-0. Product ID: 3-00444. Molecular formula: C31H52N2O23. Mole weight: 820.74. Properties: E- and P-selectin ligand with higher affinity than sialyl Lewis a. Reference: J. Appl. Physiol., 82, 1058, 1997; J. Biol. Chem., 269, 1595, 1994. Categories: 3-Sialyl-Lewis x.
3-Sialyl Lewis X
It is an important antigen, which binds to the endothelial adhesion molecule E-selectin. Synonyms: S Lex; Sialyl Lewis X; NeuNAc-a2-3Gal-b1-4(Fuc-a1-3)GlcNAc; Neu5Ac2-α-3Gal1-b-4[Fuc1-α-3]GlcNAc; O-(5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic Acid)-2-α-3-O-(b-D-galactopyranosyl)-1-b-4-O-[(α-L-fucopyranosyl)-1-α-3]-2-acetamido-2-deoxy-D-glucopyranose]; SSEA 1; 3'-Sialyl-Lewis-X tetrasaccharide. Grades: ≥95%. CAS No. 98603-84-0. Molecular formula: C31H52N2O23. Mole weight: 820.74.
3'-Sialyl Lewis X 16-sp-biotin
3'-Sialyl Lewis X 16-sp-biotin is a highly specialized and state-of-the-art compound playing a pivotal role in the identification and examination of specific maladies or pharmaceutical targets. By selectively adhering to precise receptors or proteins involved in the intricate domains of inflammation, oncology is and cellular adhesion, it emerges as an invaluable instrument in propelling compound research forward. Synonyms: NeuNAca2-3-Galb1-4(Fuca1-3)GlcNAcb1-NHCOCH2NHCO(CH2)12NH-Biotin; NeuNAca2-3-Galb1-4(Fuca1-3)GlcNAcb1-NH-(16 atom spacer)-Biotin. Grades: 95%. Molecular formula: C56H95N7O26S. Mole weight: 1314.45.
3'-Sialyl Lewis X 1-N-methyl-N-hydroxyethylamine
3'-Sialyl Lewis X 1-N-methyl-N-hydroxyethylamine is an exquisitely crafted biomedicine worthy of our attention. Its application spans across a diverse range of inflammatory diseases and cancers, proving its versatility and efficacy. By diligently targeting selectins, it skillfully halts their nefarious interaction with cell surface glycoproteins. Consequently, behold the magnificent reduction in adhesion and migration of inflammatory cells and the commendable suppression of cancer metastasis. Grades: 95%. Molecular formula: C34H60N4O23. Mole weight: 892.85.
3'-Sialyl Lewis X 4-sp-biotin
3'-Sialyl Lewis X 4-sp-biotin, an incredibly potent biomedicine tool, is extensively employed in academic research to elucidate the complex mechanisms behind the pivotal role played by the 3'-Sialyl Lewis X antigen in various cellular adhesion and recognition processes. By facilitating the comprehensive examination of selectins and their corresponding ligands, this product significantly contributes to our comprehension of pathologies characterized by erroneous cell adhesion, including malignancies and inflammatory disorders. Molecular formula: C42H71N7O26S. Mole weight: 1122.11.
3-Sialyl Lewis X b 1-O-n-pentylamine
3-Sialyl Lewis X b 1-O-n-pentylamine is a prominent compound in the field of compound, exhibiting extraordinary efficacy in research of selectively targeting and combating various diseases. Molecular formula: C36H63N3O24. Mole weight: 921.89.
3'-Sialyl Lewis X b 1-O-n-pentylamine
3'-Sialyl Lewis X b 1-O-n-pentylamine, an extraordinary biomedical compound, stands at the forefront of targeting selectins in the formidable battle against inflammatory ailments. This compound, birthed from sialylated glycans, unravels its true essence by showcasing unparalleled affinities with selectins, thereby intervening in cell adhesion inhibition and inflammation abatement. This multifaceted marvel, possessing a plethora of therapeutic applications, emerges as an invaluable instrument for the discerning minds actively engaged in biomedical drug discovery and development endeavors. Molecular formula: C36H63N3O24. Mole weight: 921.89.
3-Sialyl Lewis X- biotin
3-Sialyl Lewis X-biotin is a compound used for the detection and study of cell adhesion molecules involved in inflammation, cancer metastasis is and leukocyte recruitment. It is an effective tool for labeling and visualizing selectin ligands. This compound is widely employed in research related to drugs targeting selectin-mediated cell adhesion and therapies for diseases like cancer and inflammation. Molecular formula: C56H95N7O26S. Mole weight: 1314.45.
3-Sialyl Lewisx-BSA
3-Sialyl Lewis x-HSA
3-Sialyl Lewis X-PAA-biotin
3-Sialyl Lewis X-sp-biotin
3-Sialyl Lewis X-sp-biotin is a profoundly potent biotinylated glycan probe, emerging as an indispensable tool in the realm of cutting-edge biomedical exploration. With its exclusive affinity for sialyl Lewis X glycan formations, it propels the scientific community into uncharted territories of comprehending cell adhesion, inflammatory cascades is and intricate interactions between metastatic cancer cells. This invaluable asset paves the way for delving into the enigmatic realm of glycan-mediated biological phenomena, opening doors to transformative therapeutic interventions designed to combat debilitating afflictions, exemplified by cancer and inflammation. Molecular formula: C50H84N6O26S. Mole weight: 1217.29.
3'-Sialyl Lewis X-sp-biotin
3'-Sialyl Lewis X is a carbohydrate antigen mainly found on tumor cells as well as on leukocytes that play important roles in the immune response. 3'-Sialyl Lewis X-sp-biotin is a biotin-conjugated small molecule that specifically recognizes and binds to 3'-Sialyl Lewis X, making it a valuable tool in diagnostics and biomedical research related to cancer and inflammation. Grades: 95%. Molecular formula: C50H84N6O26S. Mole weight: 1217.29.
6-Sulfo Sialyl Lewis X Methyl Glycoside Sodium Salt
Sialyl Lewis X derivative. Synonyms: [Methyl O-[5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic Acid)-2-α-3-O-β-D-galactopyranosyl]-1-β-4-O-[(α-L-fucopyranosyl)-1-α-3]-2-acetamido-2-deoxy-6-sulfo-D-glucopyranoside] Sodium Salt. Molecular formula: C32H52N2NaO26S. Mole weight: 936.82.
Penta-O-benzyl Sialyl Lewis X Methyl Glycoside Methyl Ester
Sialyl Lewis X derivative, an antigen which binds to endothelial adhesion molecule, E-selectin. Synonyms: Methyl 4-[O-(N-Acetyl-1-methyl-α-neuraminosyl)-3-O-[6-O-(phenylmethyl)-β-D-galactopyranosyl]-3-O-[6-deoxy-2,3,4-tris-O-(phenylmethyl)-α-L-galactopyranosyl-]-2-(acetylamino)-2-deoxy-6-O-(phenylmethyl)-β-D-glucopyranoside. Molecular formula: C68H86N2O23. Mole weight: 1299.41.
Sialyl Lewisa (Slea)-BSA
Sialyl-Lewis X
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) [1]. Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability to inhibits CD62-mediated neutrophil recruitment to sites of inflammation [2]. Uses: Scientific research. Group: Natural products. Alternative Names: sLeX. CAS No. 98603-84-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W020790.
Sialyl Lewisx-b-methyl glycoside
Sialyl Lewisx-b-methyl glycoside is a remarkable biomedical compound, demonstrating profound utility in studying maladies stemming from aberrant immune responses and leukocyte mobility. Proficiently inhibiting selectin activity, this product diligently impairs the affinity of these adhesion molecules towards ligands. Molecular formula: C32H54N2O23. Mole weight: 834.77.
Sialyl Lewis X ceramide
Sialyl Lewis X cholesterol
Sialyl Lewis X methyl glycoside
Sialyl Lewis X methyl glycoside - a synthetic carbohydrate molecule employed in biomedical research - provides unique insight into the molecular mechanisms underlying selectin-ligand interactions, critical for the pathogenesis of multifarious diseases, including cancer and inflammation. Synonyms: Sialyl Lewisx-β-methyl glycoside; Neu5Ac-a-2-3-Gal-b-1-4[Fuc-a-1-3]GlcNAc-b-Ome; Methyl O-[5-acetamido-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonic acid)-2-a-3-O-b-D-galactopyranosyl]-1-b-4-O-[(a-L-fucopyranosyl)-1-a-3]-2-acetamido-2-deoxy-b-D-glucopyranoside; Methyl 3-O-(alpha-L-fucopyranosyl)-4-O-[3-O-(N-acetyl-alpha-neuraminosyl)-beta-D-galactopyranosyl]-2-(acetylamino)-2-deoxy-beta-D-glucopyranoside. Grades: 98%. CAS No. 141612-87-5. Molecular formula: C32H54N2O23. Mole weight: 834.77.
Sialyl Lewis X pentaose
Sialyl Lewis X pentaose is a carbohydrate compound used in biomedical field as a binding compound for specific receptors involved in cell adhesion and migration. It is primarily utilized for studying the interactions between selectin proteins and cancer cells aiding in the development of targeted therapies for metastatic cancers. Synonyms: Neu5Ac-a-2-3-Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-1-3-Gal. Molecular formula: C37H61N2O28Na. Mole weight: 1004.87.
2-Deoxy-1,3,4,6-tetra-O-pivaloyl-D-glucopyranose
2-Deoxy-1,3,4,6-tetra-O-pivaloyl-D-glucopyranose, a critical molecule utilized in peptide synthesis as an amino acid shielding agent, holds immense value in the realm of biomedical research. The scientific community also acknowledges its significance in generating therapeutically potent sialyl Lewis X mimetics that deter cancer cell adhesion. The diverse applications of this compound cement its position as an essential component for achieving successful outcomes in biomedicine. Molecular formula: C26H44O9. Mole weight: 500.64.
An intermediate in the synthesis of Sialyl Lewis X. Synonyms: Methyl O-6-Deoxy-2,3,4-tris-O-(phenylmethyl)-α-L-galactopyranosyl-(1?3)-O-[6-O-(phenylmethyl)-β-D-galactopyranosyl-(1?4)]-2-(acetylamino)-2-deoxy-6-O-(phenylmethyl)-α-D-glucopyranoside. Molecular formula: C56H67NO15. Mole weight: 994.13.
An intermediate in the synthesis of Sialyl Lewis X. Molecular formula: C42H51NO13. Mole weight: 777.85.
Lacto-N-Biosidase, Recombinant
Lacto-N-Biosidase may be used during glycoprotein analysis to better study the structure and function of glycoprotein and glycolipid sugar chains. This product can be used for specific oligosaccharide hydrolysis of type-I chain oligosaccharides, producing lacto-N-biose (Gal β 1-3 GlcNAc) as a byproduct, but not oligosaccharide hydrolysis of type-II chain oligosaccharides. As a result, Lacto-N-Biosidase can be used to distinguish type-I versus type-II glycoprotein as well as glycolipid sugar chains. When used in conjunction with α -1,3/4-Fucosidase, Lacto-N-Biosidase can also help distinguish Sialyl-Lewis x and Sialyl-Lewis a structures. Applications: Specific hydrolysis of oligosaccharides with type-i sugar chains and production of byproduct lacto-n-biose (gal β 1-3 glcnac). Group: Enzymes. Synonyms: Oligosaccharide lacto-N-biosylhydrolase; Lacto-N-Biosidase. Lacto-N-Biosidase. Mole weight: 60 kDa (SDS-PAGE). Form: Solution in 50 mM sodium acetate buffer, pH 5.5, containing 0.05% Brij-58. Source: Streptomyces sp. 142. Oligosaccharide lacto-N-biosylhydrolase; Lacto-N-Biosidase. Cat No: NATE-0855.
Lacto-N-fucopentaose II
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy [1]. Uses: Scientific research. Group: Natural products. Alternative Names: LNFP II. CAS No. 21973-23-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7575.
Lactosamine
Lactosamine forms the backbone of several cell surface glycans such as sialylated glycans or keratin sulfates. Also, it is a basic structural element of Lewis type, and human milk oligosaccharides. Group: Biochemicals. Grades: Highly Purified. CAS No. 13000-25-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H23NO10, Molecular Weight: 341.31. US Biological Life Sciences.
Worldwide
N-Acetyllactosamine
N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Acetyl-D-lactosamine. CAS No. 32181-59-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126854.
Native Human Cancer Antigen 19-9
Cancer Antigen 19-9 is a tumor marker elevated in blood of patients with carcinoma of the gastro-intestinal tract. Primarily used distinguishing pancreatic cancer from pancreatitis, CA 19-9 is not sufficiently specific for use as a cancer screening test. The specificity for pancreatic cancer increases with increasing levels, high levels showing a specificity of >97% for tumor presence. CA 19-9 can be elevated in many types of gastrointestinal cancer, such as colorectal cancer, esophageal cancer and hepatocellular carcinoma. A group of mucin type glycoprotein Sialosyl Lewis Antigens (SLA), such as CA19-9 and CA19-5, have come to be recognized as circulating cancer associated a...plications: Diagnostic controls; calibrators & standards; immunoassays; testing/assay validation; life science; validation studies; manufacturing; tumor markers. Group: Others. Synonyms: Tumor Marker 19-9; CA 19-9; Cancer Antigen 19-9; carbohydrate antigen 19-9; Sialylated Lewis (a) Antigen. Purity: High Purity - Low Cross Contamination of other cancer antigens (Gel filtration & ion-exchange chromatography). Activity: Typically > 500 kU/mL. Stability: 2 years. Appearance: Clear and Colorless. Storage: Store at -20°C. Form: Liquid in phosphate buffered saline, pH 7.4 with sucrose and 0.05% sodium azide. Source: Human Liver Metastases. Species: Human. Tumor Marker 19-9; CA 19-9
Native Human Cancer Antigen 242
CA-242 is a tumor marker for sialylated Lewis carbohydrates associated with adenocarcinomas and e-selectin mediated metastatic risk. It has been found to be an early detector of Pancreatic Cancer. Applications: Diagnostic controls; calibrators & standards; immunoassays; clinical chemistry; testing/assay validation; life science; elisa; blotting; manufacturing; tumor markers. Group: Others. Synonyms: Cancer Antigen 242; CA-242. Activity: > 25 kU/mL. Stability: 2 years. Storage: Store at -20°C. Form: Liquid in PBS, pH 7.4. Source: Human Cell Culture. Species: Human. Cancer Antigen 242; CA-242. Cat No: NATE-0955.