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| Product | Description | |
|---|---|---|
| Sialyl-Lewis X | Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) [1]. Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability to inhibits CD62-mediated neutrophil recruitment to sites of inflammation [2]. Uses: Scientific research. Group: Natural products. Alternative Names: sLeX. CAS No. 98603-84-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W020790. |  |
| 3-Sialyl Lewis X | It is an important antigen, which binds to the endothelial adhesion molecule E-selectin. Synonyms: S Lex; Sialyl Lewis X; NeuNAc-a2-3Gal-b1-4(Fuc-a1-3)GlcNAc; Neu5Ac2-α-3Gal1-b-4[Fuc1-α-3]GlcNAc; O-(5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosylonic Acid)-2-α-3-O-(b-D-galactopyranosyl)-1-b-4-O-[(α-L-fucopyranosyl)-1-α-3]-2-acetamido-2-deoxy-D-glucopyranose]; SSEA 1; 3'-Sialyl-Lewis-X tetrasaccharide; O-(N-Acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→3)]-2-(acetylamino)-2-deoxy-D-glucose; 3'-Sialyl-Lewis X; Sialyl Lex tri; Sialyl-Lewis X; SLex. Grade: ≥95%. CAS No. 98603-84-0. Molecular formula: C31H52N2O23. Mole weight: 820.74. |  |
| Ac5GalNTGc | Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160109. | |
| Lacto-N-Biosidase, Recombinant | Lacto-N-Biosidase may be used during glycoprotein analysis to better study the structure and function of glycoprotein and glycolipid sugar chains. This product can be used for specific oligosaccharide hydrolysis of type-I chain oligosaccharides, producing lacto-N-biose (Gal β 1-3 GlcNAc) as a byproduct, but not oligosaccharide hydrolysis of type-II chain oligosaccharides. As a result, Lacto-N-Biosidase can be used to distinguish type-I versus type-II glycoprotein as well as glycolipid sugar chains. When used in conjunction with α -1,3/4-Fucosidase, Lacto-N-Biosidase can also help distinguish Sialyl-Lewis x and Sialyl-Lewis a structures. Applications: Specific hydrolysis of oligosaccharides with type-i sugar chains and production of byproduct lacto-n-biose (gal β 1-3 glcnac). Group: Enzymes. Synonyms: Oligosaccharide lacto-N-biosylhydrolase; Lacto-N-Biosidase. Lacto-N-Biosidase. Mole weight: 60 kDa (SDS-PAGE). Form: Solution in 50 mM sodium acetate buffer, pH 5.5, containing 0.05% Brij-58. Source: Streptomyces sp. 142. Oligosaccharide lacto-N-biosylhydrolase; Lacto-N-Biosidase. Cat No: NATE-0855. |  |
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