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| Product | Description | |
|---|---|---|
| Sirtinol | Sirtinol is a known inhibitor of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5 and exhibits anticancer properties. Group: Biochemicals. Alternative Names: 2-[[ (2-hydroxy-1-naphthalenyl) methylene]amino]-N- (1-phenylethyl) -benzamide; Sir Two Inhibitor Naphthol. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 10mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Sirtinol | Sirtinol is a SIRT inhibitor. Sirtinol significantly increased the acetylation of p53, which has been reported to be a target of SIRT1/2. Sirtinol significantly increased the G1 phase of the cell cycle. Synonyms: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide; 2-{[(2-hydroxy-1-naphthyl)methylene]amino}-N-(1-phenylethyl)benzamide; 2-[(2-hydroxynaphthalen-1-yl)methylideneamino]-N-(1-phenylethyl)benzamide; Sir Two Inhibitor Naphthol; (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide; 2-(((2-Hydroxynaphthalen-1-yl)methylene)amino)-N-(1-phenylethyl)benzamide; 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide; (E)-2-(((2-HYDROXYNAPHTHALEN-1-YL)METHYLENE)AMINO)-N-(1-PHENYLETHYL)BENZAMIDE; {2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]}-N-(1-phenethyl)benzamide (Sirtinol. Grades: 0.98. CAS No. 410536-97-9. Molecular formula: C26H22N2O2. Mole weight: 394.474. |  |
| Sirtinol | Sirtinol is a sirtuin (SIRT) inhibitor, with IC 50 s of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 410536-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13515. |  |
| Sirtinol (SIRT2 Inhibitor Naphthol) | Cell-permeable. A selective sirtuin deacetylase inhibitor with IC50 values of 38, 68 and 131uM for SIRT2, Sir2p and SIRT1 respectively. Sirtinol has no effect on HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells. Group: Biochemicals. Alternative Names: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Sirtinol (Sir Two Inhibitor Naphthol, 2-N-(1-phenethyl)benzamide) | Specific cell permeable SIRT1 (sirtuin-1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer. Group: Biochemicals. Alternative Names: Sir Two Inhibitor Naphthol, 2--N-(1-phenethyl)benzamide. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
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