Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Sitravatinib | Sitravatinib, a new inhibitor of tyrosine kinase, has been studied to have effective in inhibiting tyrosine kinases receptors involved in driving sarcoma cell growth. It is still under a phase II trial for Non small cell lung cancer. IC50: 3980 nmol/L. Uses: Sitravatinib has been studied to have effective in inhibiting tyrosine kinases receptors involved in driving sarcoma cell growth. it is still under a phase ii trial for non small cell lung cancer. Synonyms: MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; Sitravatinib. Grades: 98%. CAS No. 1123837-84-2. Molecular formula: C33H29F2N5O4S. Mole weight: 629.68. |  |
| Sitravatinib | Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC 50 s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively [1]. Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD516; MG-516. CAS No. 1123837-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16961. |  |
Our database is helping our users find suppliers everyday.
