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| Product | Description | |
|---|---|---|
| SKF89976A | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF89976A; SKF 89976A; SKF-89976A. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 85375-15-1. Molecular formula: C22H25NO2. Mole weight: 335.45. Purity: >98%. IUPACName: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid. Canonical SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O. Product ID: ACM85375151-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SKF89976A HCl | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF89976A HCl; SKF 89976A; SKF-89976A; SKF89976A hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 85375-85-5. Molecular formula: C22H26ClNO2. Mole weight: 371.9. Purity: >98%. IUPACName: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride. Canonical SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O.[H]Cl. Product ID: ACM85375855-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF89976A hydrochloride | SKF89976A hydrochloride is a selective GABA transporter ( GAT-1 ) inhibitor with IC 50 s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d,l-SKF89976A hydrochloride. CAS No. 85375-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100228A. |  |
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