Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| SKI-I | SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK) , with an IC 50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 ( IC 50 =11 μM). SKI-I induces apoptosis in tumor cell lines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 306301-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115735. |  |
| SKI-II, Sphingosine Kinase Inhibitor (4- [ [4- (4-Chlorophenyl) -2-thiazolyl] amino] phenol) | Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5uM, with no inhibition against ERK2, PI3-kinase, or PKCa at concentrations up to 60uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 312636-16-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| SKI-I, Sphingosine Kinase Inhibitor (5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide) | Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 306301-68-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| SKI II | 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins. Synonyms: SphK-I2; SKI-II; SKI II. Sphingosine kinase inhibitor II. Grades: >98%. CAS No. 312636-16-1. Molecular formula: C15H11ClN2OS. Mole weight: 302.78. |  |
| SKI II | SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312636-16-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13822. | |
Our database is helping our users find suppliers everyday.
