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| Product | Description | |
|---|---|---|
| SMER 3 | SMER 3. Group: Biochemicals. Grades: Purified. CAS No. 67200-34-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SMER 3 | SMER 3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30), and also a small molecule enhancer of rapamycin (SMER). SMER 3 directly targets the MET30 subunit and induces the expression of MET genes. SMER 3 inhibits cell proliferation. Synonyms: SMER3; SMER-3; SMER 3; 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one. Grades: ≥98% by HPLC. CAS No. 67200-34-4. Molecular formula: C11H4N4O2. Mole weight: 224.18. |  |
| Met30 Antagonist, SMER3 | The Met30 Antagonist, SMER3 controls the biological activity of Met30. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. |  |
| SMER3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one | 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Oxoindeno<1,2-e>furazano<3,4-b>pyrazin. Product Category: Heterocyclic Organic Compound. CAS No. 67200-34-4. Molecular formula: C11H4N4O2. Mole weight: 224.18. Purity: 0.96. IUPACName: SMER3. Canonical SMILES: C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O. Density: 1.665 g/cm³. Product ID: ACM67200344. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SMER28 | SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. Uses: Scientific research. Group: Signaling pathways. CAS No. 307538-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100200. |  |
| SMER28 | SMER28 is a small-molecule modulator of autophagy that increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntington's, Parkinson's, and Alzheimer's diseases. It enhances reprogramming of mouse fibroblasts into induced neural stem cell-like cells. Synonyms: N-Allyl-6-bromoquinazolin-4-amine; SMER-28; 6-bromo-N-prop-2-enylquinazolin-4-amine. Grades: >98%. CAS No. 307538-42-7. Molecular formula: C11H10BrN3. Mole weight: 264.12. | |
| SMER 28 | SMER 28. Group: Biochemicals. Grades: Purified. CAS No. 307538-42-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline) | Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntingtons Disease (HD). Group: Biochemicals. Grades: Highly Purified. CAS No. 307538-42-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
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