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SMER28 >99% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
SMER28 SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. Uses: Scientific research. Group: Signaling pathways. CAS No. 307538-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100200. MedChemExpress MCE
SMER28 SMER28 is a small-molecule modulator of autophagy that increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntington's, Parkinson's, and Alzheimer's diseases. It enhances reprogramming of mouse fibroblasts into induced neural stem cell-like cells. Synonyms: N-Allyl-6-bromoquinazolin-4-amine; SMER-28; 6-bromo-N-prop-2-enylquinazolin-4-amine. Grades: >98%. CAS No. 307538-42-7. Molecular formula: C11H10BrN3. Mole weight: 264.12. BOC Sciences 11
SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline) Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntington’s Disease (HD). Group: Biochemicals. Grades: Highly Purified. CAS No. 307538-42-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. USBiological 1
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