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SNAP 5089 SNAP 5089. Group: Biochemicals. Grades: Purified. CAS No. 157066-77-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
SNAP 5089 SNAP 5089 is an α1A-adrenoceptor antagonist with >600-fold selectivity over other adrenoceptors (Ki = 0.35, 220, 370, 540, 800 and 1200 nM for α1A, α1B, α2C, α1D, α2B and α2A subtypes respectively and 540 nM for L-type Ca2+ channels). SNAP 5089 exhibits an inhibitory effect on noradrenalin-induced contractions in rabbit vascular and lower urinary tissues. Synonyms: 3-Pyridinecarboxylic acid, 5-[[[3-(4,4-diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-, methyl ester; Methyl 5-[[[3-(4,4-diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3-pyridinecarboxylate; SNAP5089; SNAP-5089; 2,6-Dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid N-(3-(4,4-diphenylpiperidine-1-yl)propyl]amide methyl ester. Grades: ≥95%. CAS No. 157066-76-7. Molecular formula: C36H40N4O5. Mole weight: 608.73. BOC Sciences 10

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