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| Product | Description | |
|---|---|---|
| SNS-032 | SNS-032, also known as BMS-387032, is a 2-aminothiazole-derived, small-molecule cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. CDK inhibitor SNS-032 selectively binds to CDKs 2, 7, and 9, preventing their phosphorylation and activation; inhibition of CDK activity may result in cell cycle arrest, the induction of apoptosis and decreased tumor cell proliferation in susceptible tumor cell populations. This agent has been shown to sensitize radioresistant tumor cells to ionizing radiation. Synonyms: BMS-387032; BMS 387032; SNS 032; BMS387032; SNS032; 4-Piperidinecarboxamide, N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-; N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide; N-[5-[[(5-tert-Butyloxazol-2-yl)methyl]thio]thiazol-2-yl]piperidine-4-carboxamide. Grades: >98%. CAS No. 345627-80-7. Molecular formula: C17H24N4O2S2. Mole weight: 380.53. |  |
| SNS-032 | SNS-032 (BMS-387032) is a potent and selective inhibitor of CDK2 , CDK7 , and CDK9 with IC 50 s of 38 nM, 62 nM and 4 nM, respectively. SNS-032 has antitumor effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-387032. CAS No. 345627-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10008. |  |
| SNS-032 | SNS-032. Group: Biochemicals. Alternative Names: N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide. Grades: Highly Purified. CAS No. 345627-80-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H24N4O2S2. US Biological Life Sciences. |  Worldwide |
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