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SNS-314 SNS-314. Group: Biochemicals. Alternative Names: N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]-urea. Grades: Highly Purified. CAS No. 1057249-41-8. Pack Sizes: 5mg. Molecular Formula: C18H15ClN6OS2, Molecular Weight: 430.93. US Biological Life Sciences. USBiological 3
Worldwide
SNS-314 SNS-314 is a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS-314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Synonyms: SNS314; SNS 314; N-(3-chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]Urea. Grades: >98%. CAS No. 1057249-41-8. Molecular formula: C18H15ClN6OS2. Mole weight: 430.93. BOC Sciences 11
SNS-314 mesylate SNS-314 is a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS-314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SNS314; SNS-314; SNS 314. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1146618-41-8. Molecular formula: C19H19ClN6O4S3. Mole weight: 527.03. Purity: >98%. IUPACName: N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea mesylate. Canonical SMILES: O=C(NC1=NC=C(CCNC2=C3C(C=CS3)=NC=N2)S1)NC4=CC=CC(Cl)=C4.OS(=O)(C)=O. Product ID: ACM1146618418. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
SNS-314 mesylate SNS-314 mesylate is a potent and selective aurora kinase inhibitor with IC 50 s of 9, 31, and 6 nM for aurora A, B and C, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1146618-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12003. MedChemExpress MCE
SNS-314 Mesylate SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1. Synonyms: SNS-314 Mesylate; SNS 314 Mesylate; SNS314 Mesylate. Grades: >98%. CAS No. 1146618-41-8. Molecular formula: C18H15ClN6OS2.CH4O3S. Mole weight: 527.04. BOC Sciences 10

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