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Sodium Aescinate Cas No. 20977-05-3. BOC Sciences 12
Sodium Aescinate Sodium aescinate is used as a vasoactive drug in clinical treatment. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway. Sodium aescinate can block signals transiting to downstream molecules AKT, ERK, inhibit the proliferation of breast cancer cell MCF-7 cell apoptosis and induced cell apoptosis by suppressing the activation of SRC[3]. Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[1].Sodium aescinate treatment can alleviate the symptom of polycystic ovary syndrome (PCOS) in rat model through regulating the PI3K/Akt/GSK3- β pathway[4]. Group: Biochemicals. Alternative Names: Sodium escinate; Butanoic acid,3-(acetyloxy)-2-methyl-, (5xi, 8xi, 9xi, 10xi, 16alpha, 17xi, 18xi, 21beta) -16, 21-epoxy-3- [ [O-alpha-D-glucopyranosyl- (1->4) -O- [beta-D-xylopyranosyl- (1->2) ] -beta-D-glucopyranuronosyl] oxy] -22, 24-dihydroxyolean-12-en-28-yl ester, monosodium saltthyl)phenoxy]oxane-3,4,5-triol. Grades: Highly Purified. CAS No. 20977-05-3. Pack Sizes: 20mg. Molecular Formula: C55H86NaO23, Molecular Weight: 1124.23. US Biological Life Sciences. USBiological 9
Worldwide
Sodium Aescinate Sodium aescinate, which is isolated from the herbs of Aesculus hippocastanum L, has immunity enhancing effects. Besides, it may effectively control and improve wound healing in diabetic rats via its anti-inflammatory and antioxidant activities. Sodium Aescinate can protect the lung injury induced by intestinal ischemia/reperfusion (I/R), which may be mediated by inhibiting lipid peroxidation, upregulating Bcl-2 gene protein expression, improving the ratio of Bcl-2/ Bax to inhibit lung apoptosis. Uses: Anti-inflammatory / antioxidative / antiedematous. Synonyms: Sodium escinate. Grades: 95% (mixture of isomers). CAS No. 20977-05-3. Molecular formula: C55H86NaO24. Mole weight: 1154.25. BOC Sciences 9
SodiumAescinate SodiumAescinate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SodiumAescinate. Product Category: Heterocyclic Organic Compound. CAS No. 152-94-4. Purity: 0.96. Product ID: ACM152944. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Sodium aescinate. Alfa Chemistry. 4
Aescin polysulphate sodium salt Aescin polysulphate sodium salt is a remarkable biomedical compound with anti-inflammatory and antithrombotic prowess acting as an exquisite derivative of Aescin. Molecular formula: C53H82O36S4. Mole weight: 1423.46. BOC Sciences

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