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| Product | Description | |
|---|---|---|
| Sotorasib | AMG-510 racemate. CAS No. 2252403-56-6. Product ID: 8-05044. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. |  |
| Sotorasib | Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C - mutated locally advanced or metastatic non - small cell lung cancer (NSCLC) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG-510. CAS No. 2296729-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114277. |  |
| Sotorasib racemate | Sotorasib racemate (Compound A) is an orally active racemate of Sotorasib (HY-114277), a covalent inhibitor of KRAS G12C mutant which induces adaptive feedback activation of MAPK pathway. Sotorasib racemate also exerts inhibitor activity against KRAS G12C induced cancer and can be applied to cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG-510 racemate. CAS No. 2252403-56-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114277A. | |
| AMG510 | AMG-510 is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. At the 2019 World Conference on Lung Cancer (WCLC), Amgen declared the efficacy of AMG 510 for treating non-small cell lung cancer (NSCLC) with KRAS G12 C-mutated solid tumors. Amgen also announced prospective directions for AMG510 through academic scholars and reports the few limitations on official drug release as evidence for potential investors to consider the value of AMG 510. Synonyms: AMG 510; AMG-510; Sotorasib. Grades: ≥98%. CAS No. 2252403-56-6. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. |  |
| AMG510 racemate | AMG510 is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. At the 2019 World Conference on Lung Cancer (WCLC), Amgen declared the efficacy of AMG510 for treating non-small cell lung cancer (NSCLC) with KRAS G12 C-mutated solid tumors. Amgen also announced prospective directions for AMG510 through academic scholars and reports the few limitations on official drug release as evidence for potential investors to consider the value of AMG510. Uses: Immune checkpoint inhibitors. Synonyms: AMG-510 racemate; AMG 510 racemate; Sotorasib racemate. CAS No. 2296729-00-3. Molecular formula: C30H30F2N6O3. Mole weight: 560.59. | |
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