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| Product | Description | |
|---|---|---|
| Spadin | Spadin, a natural peptide derived from a propeptide released in blood, is a potent TREK-1 channel blocker with IC 50 value of 10 nM. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis. Spadin can be used for antidepressant research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1270083-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1422. |  |
| Spadin | Spadin is a potent and brain penetrating TREK-1 channel blocker (IC50 = 71 nM) displaying antidepressant activity. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis in adult mice. Synonyms: Spadin; 1270083-24-3; Spadin (trifluoroacetate salt); HB5438; AKOS025293510; C96H142N26O22; S-1270083-24-3. CAS No. 1270083-24-3. Molecular formula: C96H142N26O22. Mole weight: 2012.34. |  |
| Spadin trifluoroacetate salt | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
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