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Spantide I Spantide I, a substance P analog, is a selective NK 1 receptor antagonist, with K i values of 230 nM and 8150 nM for NK 1 and NK 2 receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 91224-37-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1194. MedChemExpress MCE
Spantide I Spantide I is a selective NK1 receptor antagonist (Ki = 230, 8150 and > 10000 nM for rat NK1, NK2 and NK3 receptors, respectively). Uses: Analgesics. Synonyms: [D-Arg1, D-Trp7,9, Leu11]-Substance P. CAS No. 91224-37-2. Molecular formula: C75H108N20O13. Mole weight: 1497.79. BOC Sciences 9
Spantide II Spantide II is more effective as an antagonist of substance P than spantide I, but less effective in releasing histamine from mast cells. The neurotoxicity of Spantide II is negligible. Uses: Analgesics. Synonyms: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,9,Nle11)-Substance P; H-D-Lys(nicotinoyl)-Pro-β-(3-pyridyl)-Ala-Pro-3,4-dichloro-D-Phe-Asn-D-Trp-Phe-D-Trp-Leu-Nle-NH2; L-Norleucinamide, N6-(3-pyridinylcarbonyl)-D-lysyl-L-prolyl-3-(3-pyridinyl)-L-alanyl-L-prolyl-3,4-dichloro-D-phenylalanyl-L-asparaginyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-. Grades: 95%. CAS No. 129176-97-2. Molecular formula: C86H104Cl2N18O13. Mole weight: 1668.79. BOC Sciences 6

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