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Spiperone (Spiroperidol) is a potent dopamine D2 , serotonin 5-HT 1A , and serotonin 5-HT 2A antagonist. Spiperone is also a labelled ligand for neuroleptic receptors. Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway. Spiperone has the potential for the research of neurology diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Spiroperidol. CAS No. 749-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1371.
Spiperone hydrochloride
Spiperone hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 2022-29-9. Pack Sizes: 50mg. US Biological Life Sciences.
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Spiperone hydrochloride
Spiperone hydrochloride is a 5-HT2A and selective dopamine D2 receptor antagonist (Ki = 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D2, D3, D4, D1 and D5 receptors, respectively) used as an antipsychotic. It also acts as an activator of calcium-activated chloride channels (EC50 = 9.3 μM). Uses: Antipsychotic. Synonyms: 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one hydrochloride; SR-01000000261. Grades: ≥98% by HPLC. CAS No. 2022-29-9. Molecular formula: C23H26FN3O2.HCl. Mole weight: 431.94.
Spiperone hydrochloride
Spiperone hydrochloride (Spiroperidol hydrochloride) is a selective dopamine D 2 receptor ( K i values of 0.06 nM, 0.6 nM, 0.08 nM, ~350 nM, ~3500 nM for D 2 , D 3 , D 4 , D 1 and D 5 receptors, respectively) and 5-HT 2A /5-HT 1A receptor ( K i s of 1 nM/49 nM) antagonist. Spiperone hydrochloride is also a selective α1B-adrenoceptor antagonist. Spiperone hydrochloride activates calcium-activated chloride channel (CaCC). Antipsychotic and anti-inflammatory activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Spiroperidol hydrochloride. CAS No. 2022-29-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1371A.
An affinity chromatography matrix support for the biospecific purification of the D2-dopamine receptor. Group: Biochemicals. Alternative Names: CMOS. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Ethylenedioxy Spiperone Hydrochloride
Analogue of Spiperone. Group: Biochemicals. Alternative Names: 8-[3-[2-(4-Fluorophenyl)-1,3-dioxolan-2-yl]propyl]-1-phenyl- 1,3,8-triazaspiro[4.5]decan-4-one Hydrochloride. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N- (p-Aminophenethyl) spiperone
Analogue of Spiperone. Group: Biochemicals. Alternative Names: N- (p-Aminophenethyl) spiroperidol; 3-[2-(4-Aminophenyl)ethyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one. Grades: Highly Purified. CAS No. 93801-18-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N- (p-Nitrophenethyl) spiperone
Analogue of Spiperone. Group: Biochemicals. Alternative Names: 8-[4-(4-Fluorophenyl)-4-oxobutyl]-3-[2-(4-nitrophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one. Grades: Highly Purified. CAS No. 136247-18-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
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