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| Product | Description | |
|---|---|---|
| SR 144528 | SR 144528. Group: Biochemicals. Alternative Names: (1S-endo)-5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1, 3, 3-trimethylbicyclo[2. 2. 1]hept-2-yl)-1H-Pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. Molecular Formula: C29H34ClN3O, Molecular Weight: 476.05. US Biological Life Sciences. |  Worldwide |
| SR 144528 | SR 144528 is a cannabinoid (CB) receptor 2 inverse agonist with selectivity for CB2 over CB1 receptors. It antagonizes the inhibitory effects of the cannabinoid receptor agonist CP 55,940 on forskolin-stimulated adenylyl cyclase activity in cell lines permanently expressing the h CB2 receptor. It selectively blocks the mitogen-activated protein kinase activity induced by CP 55,940 in cell lines expressing h CB2. Synonyms: SR144528; SR-144528; 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]pyrazole-3-carboxamide. Grades: ≥98%. CAS No. 192703-06-3. Molecular formula: C29H34ClN3O. Mole weight: 476.1. |  |
| CB2 Inverse Agonist, SR 144528 (5- (4- chloro- 3- methylphenyl)- 1- [(4- methylphenyl)methyl]- N- [(1S, 2S, 4R)- 1, 3, 3- trimethylbicyclo[2. 2. 1]hept- 2- yl]- 1H- pyrazole-3) | A selective inverse agonist for peripheral cannabinoid (CB2) receptors (Ki = 0.6nM and 400nM for CB2 and CB1 receptors, respectively). Has been used in studies related to control of pain initiation, suppression of inflammation, and immune activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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