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| Product | Description | |
|---|---|---|
| SR 8278 | SR 8278. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 1254944-66-5. Pack Sizes: 10mg. Molecular Formula: C18H19NO3S2, Molecular Weight: 361.48. US Biological Life Sciences. |  Worldwide |
| SR 8278 | SR 8278 is a nuclear heme receptor Rev-Erbα antagonist. This compound inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM) and blocks activity of Rev-Erbα agonist GSK 4112 in HEK293 cells. SR 8278 increases expression of glucose-regulating genes, G6Pase and PEPCK in HepG2 cells. Synonyms: SR8278; SR 8278; SR-8278. 1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid ethyl ester; ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate. Grades: ≥99% by HPLC. CAS No. 1254944-66-5. Molecular formula: C18H19NO3S2. Mole weight: 361.48. |  |
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