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SSR 69071 SSR 69071. Group: Biochemicals. Grades: Purified. CAS No. 344930-95-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
SSR 69071 SSR 69071 is a potent and high affinity human leukocyte elastase (HLE) inhibitor (IC50 = 3.9 nM) that displays species-selectivity (Ki = 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase, respectively). SSR 69071 has been shown to inhibit HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduce infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Synonyms: SSR 69071; SSR69071; SSR-69071; 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: ≥98% by HPLC. CAS No. 344930-95-6. Molecular formula: C27H32N4O7S. Mole weight: 556.63. BOC Sciences 9

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