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SU 16f SU 16f. Group: Biochemicals. Grades: Highly Purified. CAS No. 251356-45-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
SU 16f SU 16f is a potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM), displaying > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. It also inhibits VEGF receptor 2. SU 16f has been shown to inhibit proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM). Synonyms: 3-[2,4-dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid; 5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; SU-16F. Grades: >98%. CAS No. 251356-45-3. Molecular formula: C24H22N2O3. Mole weight: 386.44. BOC Sciences 11

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