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| Product | Description | |
|---|---|---|
| SU14813 maleate | SU14813 maleate is a multi-targeted receptor tyrosine kinases inhibitor with IC 50 s of 50, 2, 4, 15 nM for VEGFR2 , VEGFR1 , PDGFRβ and KIT. Uses: Scientific research. Group: Signaling pathways. CAS No. 849643-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10501A. |  |
| SU14813 maleate | SU14813 maleate is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), Kit, and fms-like tyrosine kinase 3 (FLT-3). It was developed as a next-generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. It demonstrated broad and potent antitumor activity equivalent to that of sunitinib, which resulted in tumor regression, growth arrest, growth delay, and prolonged survival in established xenograft cancer models in mice. Synonyms: SU14813 maleate; SU 14813 maleate; SU-14813 maleate. Grades: >98%. CAS No. 849643-15-8. Molecular formula: C27H31FN4O8. Mole weight: 558.56. |  |
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