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SU6656 SU6656 is a Src family kinase inhibitor developed by the biotechnology company SUGEN Inc (a subsidiary of Pharmacia) in 2000. SU6656 was initially identified as a Src kinase inhibitor by virtue of its ability to reverse an effect that an activated mutant form of Src (hu SRC Y530F) has on the actin cytoskeleton, namely the formation of podosome rosettes, otherwise known as invadopodia. Subsequent studies have confirmed that SU6656 is relatively selective for Src family kinases but some additional biochemical activities have been identified including: BRSK2, AMPK, Aurora C, Aurora B, CaMKK&beta. The inhibition of these kinases in biochemical reactions in vitro does not necessarily indicate that these kinases are targets of SU6656 in cells. SU6656 has been used primarily as a research tool to investigate the function of Src family kinases in cellular signal transduction processes and biology. Synonyms: SU 6656; SU-6656. Grades: 0.98. CAS No. 330161-87-0. Molecular formula: C19H21N3O3S. Mole weight: 371.45. BOC Sciences 10
SU6656 SU6656 is a Src family kinases inhibitor with IC 50 s of 280, 20, 130, 170 nM for Src, Yes, Lyn, and Fyn, respectively. SU6656 inhibits FAK phosphorylation at Y576/577, Y925, Y861 sites. SU6656 also inhibits p-AKT. Uses: Scientific research. Group: Signaling pathways. CAS No. 330161-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0789. MedChemExpress MCE
SU6656 - CAS 330161-87-0 A potent, cell-permeable, reversible, and ATP-competitive Src family kinase inhibitor. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3

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