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| Product | Description | |
|---|---|---|
| SU9516 | SU9516 is a potent CDK2 inhibitor, with an IC 50 of 22 nM, and also shows inhibitory effects on CDK1 and CDK4, with IC 50 s of 40, 200 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 377090-84-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18629. |  |
| SU9516 | SU 9516 is a potent, selective cdk2 inhibitor (IC50 values are 0.022, 0.04, >10, >10, 18 and >100 μM for cdk2, cdk1, cdk4, PKC, p38, PDGFR and EGFR respectively). Inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest. Transcriptionally downregulates Mcl-1 and has antiproliferative, cytostatic and proapoptotic effects in vitro. Synonyms: SU-9516; SU 9516; SU9516. Grades: >98%. CAS No. 377090-84-1. Molecular formula: C13H11N3O2. Mole weight: 241.25. |  |
| SU9516 - CAS 666837-93-0 | A cell-permeable 3-substituted indolinone compound that displays anti-proliferative and proapoptotic properties in tumor cells. Group: Fluorescence/luminescence spectroscopy. |  |
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