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Sugammadex, a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periphery, is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. Synonyms: Bridion; Sugammadex sodium; 6A,6B,6C,6D,6E,6F,6G,6H-Octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-cyclodextrin. Grades: ≥ 98%. CAS No. 343306-71-8. Molecular formula: C72H104Na8O48S8. Mole weight: 2177.97.
Sugammadex
Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org25969 free acid. CAS No. 343306-71-8. Pack Sizes: 1 mg. Product ID: HY-B0079A.
Sugammadex-1
Sugammadex-1 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Molecular formula: C48H72O32I8. Mole weight: 2176.3.
Sugammadex Impurity 37
Sugammadex Impurity 37 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: 3,3'-Dithiobis-propanoic Acid; β,β'-Dithiodipropionic Acid; 2-Carboxyethyl Disulfide; DTDPA; NSC 18841; NSC 677544. Grades: 97 %. CAS No. 1119-62-6. Molecular formula: C6H10O4S2. Mole weight: 210.27.
Sugammadex-R1
Sugammadex-R1 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Org48302. Molecular formula: C69H101Na7O47S7. Mole weight: 2067.89.
Sugammadex-R12
Sugammadex-R12 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Molecular formula: C73H106Na8O48S8. Mole weight: 2192.03.
Sugammadex-R18
Sugammadex-R18 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Molecular formula: C145H208Na16O96S16. Mole weight: 4368.01.
Sugammadex-R4
Sugammadex-R4 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Org198958-2. Molecular formula: C72H104Na8O49S8. Mole weight: 2194.
Sugammadex-R5
Sugammadex-R5 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Org199425-1. Molecular formula: C72H104Na8O49S8. Mole weight: 2194.
Sugammadex-R6
Sugammadex-R6 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Org199074-1. Molecular formula: C72H104Na8O48S9. Mole weight: 2210.07.
Sugammadex-R7
Sugammadex-R7 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Org19339-1. Molecular formula: C69H101Na7O46S8. Mole weight: 2083.96.
Sugammadex sodium
Sugammadex, a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periphery, is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. Synonyms: γ-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-, sodium salt (1:8); γ-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-, octasodium salt; 6-Per-deoxy-6-per-(2-carboxyethyl)thio-γ-cyclodextrin sodium salt; Org 25969; Org25969; Org-25969; Sugammadex sodium salt. Grades: ≥95%. CAS No. 343306-79-6. Molecular formula: C72H104Na8O48S8. Mole weight: 2178.01.
Sugammadex sodium
Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex sodium shows nephroprotective effect in ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org25969. CAS No. 343306-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0079.
Monochloro Sugammadex Sodium is an impurity of Sugammadex Sodium, which is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents. And which may have many potential peri-operative benefits. Synonyms: 6-Deoxy-6-chloro-heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gammacyclodextrinSodium Salt. Grades: >95% by HPLC. Molecular formula: C69H107ClO46S7 xNa. Mole weight: 1932.47.
Mono-Hydroxy Sugammadex
Mono-Hydroxy Sugammadex is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Sugammadex Monohydroxy Impurity. CAS No. 2376607-99-5. Molecular formula: C69H101O47S7.7Na. Mole weight: 2067.87.
Monohydroxy Sugammadex Sodium
Monohydroxy Sugammadex Sodium is an impurity of Sugammadex Sodium, which is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents and may have many potential peri-operative benefits. Synonyms: Heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gamma-cyclodextrin Sodium Salt. Grades: >95% by HPLC. Molecular formula: C69H108O47S7 xNa. Mole weight: 1914.02.
Monothio Sugammadex Sodium
As an impurity of Sugammadex Sodium, Monothio Sugammadex Sodium is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents. And it may have many potential peri-operative benefits. Synonyms: 6-Deoxy-6-thio-heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gammacyclodextrin. Grades: 97%. Molecular formula: C69H108O46S8 xNa. Mole weight: 1930.09.
Monothio Sugammadex Sodium
Monothio Sugammadex Sodium. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS002373. Format: Neat.
6-deoxy-6-iodo-gamma-cyclodextrin
Sugammadex Impurity 32 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Sugammadex Impurity 32; Octakis-(6-deoxy-6-iodo)-γ-cyclodextrin; 6-per-deoxy-6-per-iodo-γ-cyclodextrin; OCTAKIS-6-IODO-6-DEOXY-GAMMA-CYCLODEXTRIN; 6A,6B,6C,6D,6E,6F,6G,6H-Octadeoxy-6A,6B,6C,6D,6E,6F,6G,6H-octaiodo-γ-cyclodextrin. Grades: > 95%. CAS No. 168296-33-1. Molecular formula: C48H72I8O32. Mole weight: 2176.29.
γ-Cyclodextrin
γ-Cyclodextrin is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Cyclooctapentylose; gamma-Cyclodextrin; Cyclooctaamylose; Cyclomaltooctaose. Grades: ≥ 98%. CAS No. 17465-86-0. Molecular formula: C48H80O40. Mole weight: 1297.12.
Octakis(6-deoxy-6-bromo)-gamma-cyclodextrin
Sugammadex Impurity 3 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: octakis(6-bromo-6-deoxy)-γCD; Octakis(6-deoxy-6-bromo)-gamma-cyclodextrin; OCTAKIS-6-BROMO-6-DEOXY-GAMMA-CYCLODEXTRIN; Sugammadex Impurity 4. Grades: > 90%. CAS No. 53784-84-2. Molecular formula: C48H72O32Br8. Mole weight: 1800.30.
Octakis(6-deoxy-6-chloro)-gamma-cyclodextrin
Sugammadex Impurity 14 is an impurity of sugammadex, a cyclodextrin agent indicated for the treatment of neuromuscular blockade induced by rocuronium and vecuronium. It inactivates rocuronium by encapsulating (chelating) the free molecule to form a stable complex. Synonyms: Sugammadex Impurity 14; Octakis-(6-chloro-6-deoxy)-gamma-cyclodextrin; 6A,6B,6C,6D,6E,6F,6G,6H-Octachloro-6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy-γ-cyclodextrin. Grades: > 90%. CAS No. 173094-60-5. Molecular formula: C48H72Cl8O32. Mole weight: 1444.67.
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