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Sulindac. Group: Biochemicals. Grades: Purified. CAS No. 38194-50-2. Pack Sizes: 100mg. US Biological Life Sciences.
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Sulindac
Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac also is an immunomodulatory agent. Sulindac can be used for the research of arthritis of the spine, gouty arthritis and kinds of cancer including colorectal cancer (CRC) and lung cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-231. CAS No. 38194-50-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0008.
Sulindac
Sulindac. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SULINOL;SULINDAC;SULREUMA;MK-231;(z)-5-fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1h-indene-3-ac;1h-indene-3-aceticacid,5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methyle;Aclin;arthrocine. Product Category: Heterocyclic Organic Compound. Appearance: Yellow solid. CAS No. 38194-50-2. Molecular formula: C20H17FO3S. Mole weight: 356.41. Density: 1.38 g/cm³. ECNumber: 253-819-2. Product ID: ACM38194502. Alfa Chemistry ISO 9001:2015 Certified.
Sulindac
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: MK-231, (1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid, Reumofil, cis-5-fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid, Sulreuma, Aflodac, Algocetil, Sulinol, Clinoril, Arthrocine, Clisundac, Citireuma, Artribid,Sulindac, Reumyl, Sudac.
A non-steroidal anti-inflammatory agent. An anti-inflammatory. Group: Biochemicals. Alternative Names: (1Z) -5-Fluoro-2-methyl-1-[ (4- (methylsulfinyl) phenyl]methylene]-1H-indene-3-acetic Acid, MK-231, Aflodac, Algocetil, Sulinol, Sulreuma. Grades: Highly Purified. CAS No. 38194-50-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Sulindac intermediate
Sulindac intermediate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SULINDAC INTERMEDIATE;6-FLUORO-2-METHYL-3-(P-METHYLTHIOBENZYL)-1H-INDENE;5-FLUORO-2-METHYL-1-(4-METHYLSULFANYL-BENZYL)-1H-INDENE;6-FLUORO-2-METHYL-3-(4-METHYLSULFANYL-BENZYL)-1H-INDENE. Product Category: Heterocyclic Organic Compound. CAS No. 41201-60-9. Molecular formula: C18H17FS. Mole weight: 284.3909832. Purity: 0.96. IUPACName: 6-fluoro-2-methyl-3-[(4-methylsulfanylphenyl)methyl]-1H-indene. Canonical SMILES: CC1=C(C2=C(C1)C=C(C=C2)F)CC3=CC=C(C=C3)SC. Density: 1.18g/cm³. Product ID: ACM41201609. Alfa Chemistry ISO 9001:2015 Certified.
Sulindac Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Sulindac Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Sulindac Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC 50 of 20.2 μM for γ 42 -secretase activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: cis-Sulindac sulfide. CAS No. 49627-27-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1786.
Sulindac sulfide
Sulindac sulfide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SULINDAC SULPHIDE;(Z)-5-FLUORO-2-METHYL-1-[P-(METHYLTHIO)BENZYLIDENE]INDENE-3-ACETIC ACID;(Z)-5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid;(Z)-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-1H-INDEN-3-YLACETIC ACID;5-Fluor. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 49627-27-2. Molecular formula: C20H17FO2S. Mole weight: 340.41. Product ID: ACM49627272. Alfa Chemistry ISO 9001:2015 Certified.
Sulindac Sulfide
Melting Point: 184-186°C. Group: Biochemicals. Grades: Highly Purified. CAS No. 32004-67-4. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Sulindac Sulfide - CAS 32004-67-4
A cell-permeable, active metabolite of Sulindac. Group: Fluorescence/luminescence spectroscopy.
Sulindac sulfone
?94% (HPLC), (solid or powder). Group: Fluorescence/luminescence spectroscopy.
Sulindac sulfone
Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59973-80-7. Pack Sizes: 1 mg. Product ID: HY-B1787.
Sulindac Sulfone
An active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
(R)-Sulindac
(R)-Sulindac. Group: Biochemicals. Alternative Names: (1Z) -5-Fluoro-2-methyl-1- [ [4- [ (R) -methylsulfinyl] phenyl] methylene] -1H-indene-3-acetic acid; R-Sulindac sulfoxide. Grades: Highly Purified. CAS No. 190967-68-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H17FO3S. US Biological Life Sciences.
Worldwide
(S)-Sulindac
(S)-Sulindac. Group: Biochemicals. Alternative Names: (1Z) -5-Fluoro-2-methyl-1- [ [4- [ (S) -methylsulfinyl] phenyl] methylene] -1H-indene-3-acetic acid; S-Sulindac sulfoxide. Grades: Highly Purified. CAS No. 149116-77-8. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H17FO3S. US Biological Life Sciences.
Worldwide
(Z)-Sulindac Sulfide
(Z)-Sulindac Sulfide is a highly potent anti-inflammatory compound, finding essential application in the research of diverse ailments like colorectal cancer, familial adenomatous polyposis (FAP) and numerous inflammatory disorders. This compound's remarkable mechanism entails the inhibition of cyclooxygenase (COX) enzymes, leading to a reduction in prostaglandin production and consequent suppression of inflammatory responses. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylthio)?phenyl]?methylene]?-, (1Z)?-; cis-Sulindac sulfide. Grade: 95%. CAS No. 49627-27-2. Molecular formula: C20H17FO2S. Mole weight: 340.418.
Exisulind
An active metabolite of Sulindac. Exisulind induces apoptosis through the activation of protein kinase G (PKG). Uses: Anticarcinogenic agents. Synonyms: Sulindac sulfone; Aptosyn; Prevatec; FGN-1; cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid; (Z)-2-(5-fluoro-2-methyl-1-(4-(methylsulfonyl)benzylidene)-1H-inden-3-yl)acetic acid. CAS No. 59973-80-7. Molecular formula: C20H17FO4S. Mole weight: 372.41.
Exisulind
Exisulind is an inactive metabolite of the nonsteroidal, anti-inflammatory agent sulindac [1]. Exisulind inhibits aldose reductase with an IC 50 of 367 nM in vitro and may contribute to the beneficial pharmacological effects of sulindac on type 2 diabetic complications [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59864-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13633.
K-8012
K-8012, a sulindac (HY-B0008) analog, is a potent antagonist of RXRa. The IC 50 value for K-8012 to inhibit 9-cis-RA-induced Gal4-RXRa-LBD trans-activation were about 9.2 μM. K-8012 exerts improved anticancer activity over sulindac in a RXRa-dependent manner. K-8012 exhibits activity in inhibiting the tRXRa-mediated PI3K/AKT signaling pathway. K-8012 induces apoptosis and inhibits AKT activation by preventing tRXRa from binding to p85a [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346513-17-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121435.
Nonsteroidal Anti-Inflammatory Compound Library
A unique collection of 530 nonsteroidal anti-inflammatory related compounds can be used for HTS and HCS; - Contains common NSAIDs, such as aspirin, indomethacin, ibuprofen, Sulindac, Piroxicam, etc. ?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4710. Categories: Nonsteroidal Anti-Inflammatory Compounds Libraries.
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