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| Product | Description | |
|---|---|---|
| Sulprostone | ?95% (HPLC), oil. Group: Fluorescence/luminescence spectroscopy. |  |
| Sulprostone | Sulprostone. Group: Biochemicals. Grades: Purified. CAS No. 60325-46-4. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Sulprostone | Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHB 286; CP-34089; ZK-57671. CAS No. 60325-46-4. Pack Sizes: 1 mg (10.74 mM * 200 μL in Methyl acetate). Product ID: HY-19360. |  |
| H-1152 Dihydrochloride | H-1152 Dihydrochloride is a cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases. It inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. It selectively blocks lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS (IC50=2.5nM) in NT-2 cells. Synonyms: (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolynyl)sulfonyl]homopiperazine Dihydrochloride; 5-[[(2S)-Hexahydro-2-Methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-Methylisoquinoline dihydrochloride; 4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrochloride. Grade: >98 %. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34. |  |
| L-798106 | L-798106 is a potent and selective prostanoid receptor EP3-selective antagonists. L-798106 has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. L-798106 successfully blocks the actions of sulprostone, an EP3-selective agonist. L-798106 was useful in showing that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity. Group: Biochemicals. Alternative Names: (2E) -N-[ (5-Bromo-2-methoxyphenyl) sulfonyl]-3-[2- (2-naphthalenylmethyl) phenyl]-2-propenamide; CM 9; GW 671021. Grades: Highly Purified. CAS No. 244101-02-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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