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| Product | Description | |
|---|---|---|
| Sulprostone | ?95% (HPLC), oil. Group: Fluorescence/luminescence spectroscopy. |  |
| Sulprostone | Sulprostone. Group: Biochemicals. Grades: Purified. CAS No. 60325-46-4. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Sulprostone | Sulprostone is a synthetic PGE2 analog that acts as a selective EP3 and EP1 receptor agonist (Ki = 0.6 and 21 nM, respectively). Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity. Uses: Abortifacient agents, nonsteroidal. Synonyms: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide. CAS No. 60325-46-4. Molecular formula: C23H31NO7S. Mole weight: 465.56. |  |
| Sulprostone | Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHB 286; CP-34089; ZK-57671. CAS No. 60325-46-4. Pack Sizes: 1 mg (10.74 mM * 200 μL in Methyl acetate). Product ID: HY-19360. |  |
| Sulprostone | (Z)-7-[(1R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide. CAS No. 60325-46-4. Product ID: 8-01883. Molecular formula: C27H22BrNO4S. Mole weight: 465.56. Properties: lipid soluble methylether of dihydroartemisinin Artemisinin is sesquiterpene lactone. |  |
| H-1152 Dihydrochloride | H-1152 Dihydrochloride is a cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases. It inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. It selectively blocks lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS (IC50=2.5nM) in NT-2 cells. Synonyms: (S) - (+) -2-Methyl-1-[ (4-methyl-5-isoquinolynyl) sulfonyl]homopiperazine Dihydrochloride;5-[[(2S)-Hexahydro-2-Methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-Methylisoquinoline dihydrochloride;4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrochloride. Grades: >98 %. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34. | |
| L-798106 | L-798106 is a potent and selective prostanoid receptor EP3-selective antagonists. L-798106 has been used in multiple studies to tease out EP3 agonist activity, both in vitro and in vivo. L-798106 successfully blocks the actions of sulprostone, an EP3-selective agonist. L-798106 was useful in showing that the vascular contraction effect of PGE2 is due to its prostanoid EP3 agonist activity. Group: Biochemicals. Alternative Names: (2E) -N-[ (5-Bromo-2-methoxyphenyl) sulfonyl]-3-[2- (2-naphthalenylmethyl) phenyl]-2-propenamide; CM 9; GW 671021. Grades: Highly Purified. CAS No. 244101-02-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L-798,106 | L-798,106 is a potent and highly selective prostanoid receptor EP3 antagonist wth Ki value of 0.3 nM. It is used in prostanoid receptor signaling studies that regulates the central excitatory effects of PGE(2) and COX-2 levels on PVN neurons. It has been used to tease out EP3 agonist activity both in vitro and in vivo. It successfully blocks the EP3 agonist activity of sulprostone on guinea pig vas deferens and trachea at 0.2 μM. It attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo. Synonyms: L-798,106; L 798,106; L798,106. N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; L-798106; (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide; CM 9; GW 671021; (E)-N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide. Grades: ≥99% by HPLC. CAS No. 244101-02-8. Molecular formula: C27H22BrNO4S. Mole weight: 536.44. | |
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