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| Product | Description | |
|---|---|---|
| Suramin sodium | Heterocyclic Organic Compound. Alternative Names: SURAMINE SODIUM SALT;SURAMIN HEXASODIUM SALT;SURAMIN SODIUM;SURAMIN SODIUM SALT;1,3,5-NAPHTHYLENETRISULFONIC ACID, 8,8-[UREYLENEBIS[M-PHENYLENE-CARBONYLIMINO(4-METHYL-M-PHENYLENE)-CARBONYLIMINO]] DI- HEXASODIUM SALT;8,8-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID HEXASODIUM SALT;8,8-CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID HEXASODIUM;8,8-carbonylbisimino-3,1-phenylenecarbonylimino-(4-methyl-3,1-phenylene)carbonyliminobis-1,3,5-naphthalenetrisulfonic acid hexasodium. CAS No. 129-46-4. Molecular formula: C51H34N6Na6O23S6. Mole weight: 1429.17. Catalog: ACM129464. |  |
| Suramin Sodium | The sodium salt of Suramin which is a P2 purinergic antagonist and has been also found to have the effect in blocking the G protein binds to GPCRs so that it was studied the activity against sorts of cancer cell lines. Synonyms: Suramin hexasodium; Suramin sodium salt; Suramine sodium salt; Suramin hexasodium salt. Grades: 98%. CAS No. 129-46-4. Molecular formula: C51H34N6Na6O23S6. Mole weight: 1429.17. |  |
| Suramin sodium salt | Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor [1]. Suramin sodium salt is a potent inhibitor of sirtuins : SirT1 ( IC 50 =297 nM), SirT2 ( IC 50 =1.15 μM), and SirT5 ( IC 50 =22 μM) [2]. Suramin sodium salt is a competitive inhibitor of reverse transcriptase ( DNA topoisomerase II : IC 50 =5 μM) [3] [4]. Suramin sodium salt is a potent SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitor [5]. Suramin sodium salt efficiently inhibits IP5K and is an antiparasitic , anti-neoplastic and anti-angiogenic agent [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Suramin hexasodium salt. CAS No. 129-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0879A. |  |
| Suramin Hexasodium Salt (Germanin, NSC 34936, SK 24728) | Sodium salt of Suramin, a hepatitis C virus NS3 helicase inhibitor. Also used in the treatment of arthritis due to problematic collagen.A P2x and P2y purinergic receptor antagonist that displays antitumor, antiangiogenic and antiparasitic activities. Inhibits sirtuin 1, sirtuin 5 and topoisomerase II. Inhibits the cell surface binding of various growth factors including PDGF, EGF, FGFa and FGFb. Blocks association of G protein alpha and b/g-subunits. Potent competitive inhibitor of reverse transcriptase and protects T lymphocytes against in vitro human immunodeficiency virus infection.Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. ...lfonic Acid Hexasodium Salt; 309F; 8,8'-[Ureylenebis[m-phenylene carbonylimino (4-methyl-m-phenylene) carbonylimino]]di (1, 3, 5-naphthalenetrisulfonic Acid) Hexasodium Salt; Antrypol; BAY 205; Bayer 205; CI 1003; Fourneau 309; Germanin; Germanin (pharmaceutical); Hexasodium Sym.-bis(m-aminobenzoyl)-m-amino-p-methylbenzoyl-1-naphthylamino-4,6,8-trisulfonate) Carbamide; Moranyl; NF 060; Naganin; Naganine; Naphuride; Naphuride sodium; Sodium Suramin; Suramin Hexasodium; Suramin Sodium; Suramine Sodium. Grades: Highly Purified. CAS No. 129-46-4. Pack Sizes: 50mg, 100mg, 250mg. Molecular Formula: C??H??N?Na?O??S?, Molecular Weight: 1429.17. US Biological Life Sciences. |  Worldwide |
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