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| Product | Description | |
|---|---|---|
| Synthase,nitric oxide | Heterocyclic Organic Compound. Alternative Names: NCNOS;NCNOS, RAT;NCNOS (RAT RECOMBINANT);NITRIC OXIDE SYNTHASE (NEURONAL);NITRIC OXIDE SYNTHASE, NEURONAL RAT;NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE, CONSTITUTIVE, RAT BRAIN;NITRIC OXIDE SYNTHASE, CONSTITUTIVE, RAT NEURONAL. CAS No. 125978-95-2. Catalog: ACM125978952. |  |
| 10-deoxymethynolide synthase | The product, 10-deoxymethynolide, contains a 12-membered ring and is an intermediate in the biosynthesis of methymycin in the bacterium Streptomyces venezuelae. The enzyme also produces narbonolide (see EC 2.3.1.240, narbonolide synthase). The enzyme has 29 active sites arranged in four polypeptides (pikAI - pikAIV) with a loading domain, six extension modules and a terminal thioesterase domain. Each extension module contains a ketosynthase (KS), keto reductase (KR), an acyltransferase (AT) and an acyl-carrier protein (ACP). Not all active sites are used in the biosynthesis. Group: Enzymes. Synonyms: pikromycin PKS. Enzyme Commission Number: EC 2.3.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2187; 10-deoxymethynolide synthase; EC 2.3.1.239; pikromycin PKS. Cat No: EXWM-2187. |  |
| 10-epi-γ-eudesmol synthase | The recombinant enzyme from ginger (Zingiber zerumbet) gives 62.6% β-eudesmol, 16.8% 10-epi-γ-eudesmol, 10% α-eudesmol, and 5.6% aristolene. cf. EC 4.2.3.68 (β-eudesmol synthase) and EC 4.2.3.85 (α-eudesmol synthase). Group: Enzymes. Enzyme Commission Number: EC 4.2.3.84. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5247; 10-epi-γ-eudesmol synthase; EC 4.2.3.84. Cat No: EXWM-5247. | |
| 1,3,6,8-tetrahydroxynaphthalene synthase | Isolated from the fungus Colletotrichum lagenarium, and the bacteria Streptomyces coelicolor and Streptomyces peucetius. It only uses malonyl-CoA, without invovement of acetyl-CoA. Group: Enzymes. Synonyms: PKS1; THNS; SCO1206; RppA. Enzyme Commission Number: EC 2.3.1.233. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2181; 1,3,6,8-tetrahydroxynaphthalene synthase; EC 2.3.1.233; PKS1; THNS; SCO1206; RppA. Cat No: EXWM-2181. | |
| 1,3-β-glucan synthase | This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: 1,3-β-D-glucan-UDP glucosyltransferase; UDP-glucose-1,3-β-D-glucan glucosyltransferase; callose synthetase; 1,3-β-D-glucan-UDP glucosyltransferase; UDP-glucose-1,3-β-D-glucan glucosyltransferase; paramylon synthetas. Enzyme Commission Number: EC 2.4.1.34. CAS No. 9037-30-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2578; 1,3-β-glucan synthase; EC 2.4.1.34; 9037-30-3; 1,3-β-D-glucan-UDP glucosyltransferase; UDP-glucose-1,3-β-D-glucan glucosyltransferase; callose synthetase; 1,3-β-D-glucan-UDP glucosyltransferase; UDP-glucose-1,3-β-D-glucan glucosyltransferase; paramylon synthetase; UDP-glucose-β-glucan glucosyltransferase; GS-II; (1,3)-β-glucan (callose) synthase; β-1,3-glucan synthase; β-1,3-glucan synthetase; 1,3-β-D-glucan synthetase; 1,3-β-D-glucan synthase; 1,3-β-glucan-uridine diphosphoglucosyltransferase; callose synthase; UDP-glucose-1,3-β-glucan glucosyltransferase; UDP-glucose:(1,3)β-glucan synthase; uridine diphosphoglucose-1,3-β-glucan glucosyltransferase; UDP-glucose:1,3-β-D-glucan 3-β-D-glucosyltransferase. Cat No: EXWM-2578. | |
| (13E)-labda-7,13-dien-15-ol synthase | The enzyme from the lycophyte Selaginella moellendorffii is bifunctional, initially forming (13E)-labda-7,13-dien-15-yl diphosphate, which is hydrolysed to the alcohol. Group: Enzymes. Synonyms: labda-7,13E-dien-15-ol synthase. Enzyme Commission Number: EC 3.1.7.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3761; (13E)-labda-7,13-dien-15-ol synthase; EC 3.1.7.10; labda-7,13E-dien-15-ol synthase. Cat No: EXWM-3761. | |
| 1,4-β-D-xylan synthase | This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism. Group: Enzymes. Synonyms: uridine diphosphoxylose-1,4-β-xylan xylosyltransferase; 1,4-β-xylan synthase; xylan synthase; xylan synthetase; UDP-D-xylose:1,4-β-D-xylan 4-β-D-xylosyltransferase. Enzyme Commission Number: EC 2.4.2.24. CAS No. 37277-73-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2651; 1,4-β-D-xylan synthase; EC 2.4.2.24; 37277-73-9; uridine diphosphoxylose-1,4-β-xylan xylosyltransferase; 1,4-β-xylan synthase; xylan synthase; xylan synthetase; UDP-D-xylose:1,4-β-D-xylan 4-β-D-xylosyltransferase. Cat No: EXWM-2651. | |
| 1,4-dihydroxy-2-naphthoyl-CoA synthase | This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1 in plants), and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. Group: Enzymes. Synonyms: naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Enzyme Commission Number: EC 4.1.3.36. CAS No. 61328-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4913; 1,4-dihydroxy-2-naphthoyl-CoA synthase; EC 4.1.3.36; 61328-42-5; naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Cat No: EXWM-4913. | |
| 15-cis-phytoene synthase | Requires Mn2+ for activity. The enzyme produces 15-cis-phytoene. cf. EC 2.5.1.99, 15-trans-phytoene synthase. Group: Enzymes. Synonyms: prephytoene-diphosphate synthase (ambiguous); phytoene synthetase (ambiguous); PSase (ambiguous); geranylgeranyl-diphosphate geranylgeranyltransferase (ambiguous). Enzyme Commission Number: EC 2.5.1.32. CAS No. 50936-61-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2770; 15-cis-phytoene synthase; EC 2.5.1.32; 50936-61-3; prephytoene-diphosphate synthase (ambiguous); phytoene synthetase (ambiguous); PSase (ambiguous); geranylgeranyl-diphosphate geranylgeranyltransferase (ambiguous). Cat No: EXWM-2770. | |
| 16S rRNA pseudouridine516 synthase | The enzyme is specific for uridine516 in 16S rRNA. In vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins. Group: Enzymes. Synonyms: 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Enzyme Commission Number: EC 5.4.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5558; 16S rRNA pseudouridine516 synthase; EC 5.4.99.19; 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Cat No: EXWM-5558. | |
| 1,8-cineole synthase | Requires Mn2+ or Zn2+. Mg2+ is less effective than either. 1,8-Cineole is the main product from the enzyme with just traces of other monoterpenoids. The oxygen atom is derived from water. The reaction proceeds via linalyl diphosphate and α-terpineol, the stereochemistry of both depends on the organism. However neither intermediate can substitute for geranyl diphosphate. The reaction in Salvia officinalis (sage) proceeds via (-)-(3R)-linalyl diphosphate while that in Arabidopsis (rock cress) proceeds via (+)-(3S)-linalyl diphosphate. Group: Enzymes. Synonyms: 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Enzyme Commission Number: EC 4.2.3.108. CAS No. 110637-19-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5119; 1,8-cineole synthase; EC 4.2.3.108; 110637-19-9; 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Cat No: EXWM-5119. | |
| 1-aminocyclopropane-1-carboxylate synthase | A pyridoxal-phosphate protein. The enzyme catalyses an α,γ-elimination. Group: Enzymes. Synonyms: 1-aminocyclopropanecarboxylate synthase; 1-aminocyclopropane-1-carboxylic acid synthase; 1-aminocyclopropane-1-carboxylate synthetase; aminocyclopropanecarboxylic acid synthase; aminocyclopropanecarboxylate synthase; ACC synthase; S-adenosyl-L-methionine methylthioadenosine-lyase. Enzyme Commission Number: EC 4.4.1.14. CAS No. 72506-68-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5316; 1-aminocyclopropane-1-carboxylate synthase; EC 4.4.1.14; 72506-68-4; 1-aminocyclopropanecarboxylate synthase; 1-aminocyclopropane-1-carboxylic acid synthase; 1-aminocyclopropane-1-carboxylate synthetase; aminocyclopropanecarboxylic acid synthase; aminocyclopropanecarboxylate synthase; ACC synthase; S-adenosyl-L-methionine methylthioadenosine-lyase. Cat No: EXWM-5316. | |
| 1-deoxy-D-xylulose-5-phosphate synthase | Requires thiamine diphosphate. The enzyme forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); DXP-synthase. Enzyme Commission Number: EC 2.2.1.7. CAS No. 202218-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2034; 1-deoxy-D-xylulose-5-phosphate synthase; EC 2.2.1.7; 202218-79-9; 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); DXP-synthase. Cat No: EXWM-2034. | |
| 21S rRNA pseudouridine2819 synthase | The enzyme specifically acts on uridine2819 in 21S rRNA. Group: Enzymes. Synonyms: Pus5p. Enzyme Commission Number: EC 5.4.99.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5585; 21S rRNA pseudouridine2819 synthase; EC 5.4.99.43; Pus5p. Cat No: EXWM-5585. | |
| (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase | Isolated from Pseudomonas putida. Forms part of the pathway of camphor catabolism. Group: Enzymes. Synonyms: 2-oxo-Δ3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase. Enzyme Commission Number: EC 6.2.1.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5696; (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase; EC 6.2.1.38; 2-oxo-Δ3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase. Cat No: EXWM-5696. | |
| 2,3',4,6-tetrahydroxybenzophenone synthase | Involved in the biosynthesis of plant xanthones. Benzoyl-CoA can replace 3-hydroxybenzoyl-CoA (cf. EC 2.3.1.220, 2,4,6-trihydroxybenzophenone synthase). Group: Enzymes. Synonyms: benzophenone synthase (ambiguous); BPS (ambiguous). Enzyme Commission Number: EC 2.3.1.151. CAS No. 175780-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2091; 2,3',4,6-tetrahydroxybenzophenone synthase; EC 2.3.1.151; 175780-21-9; benzophenone synthase (ambiguous); BPS (ambiguous). Cat No: EXWM-2091. | |
| 2-(3-amino-3-carboxypropyl)histidine synthase | A [4Fe-4S] enzyme that modifies a histidine residue of the translation elongation factor 2 (EF2) via a 3-amino-3-carboxypropyl radical. The enzyme is present in archae and eukaryotes but not in eubacteria. The relevant histidine of EF2 is His715 in mammals, His699 in yeast and His600 in Pyrococcus horikoshii. Part of diphthamide biosynthesis. Group: Enzymes. Synonyms: Dph2. Enzyme Commission Number: EC 2.5.1.108. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2724; 2-(3-amino-3-carboxypropyl)histidine synthase; EC 2.5.1.108; Dph2. Cat No: EXWM-2724. | |
| (2,3-dihydroxybenzoyl)adenylate synthase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal. Group: Enzymes. Synonyms: 2,3-dihydroxybenzoate-AMP ligase. Enzyme Commission Number: EC 2.7.7.58. CAS No. 122332-73-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3269; (2,3-dihydroxybenzoyl)adenylate synthase; EC 2.7.7.58; 122332-73-4; 2,3-dihydroxybenzoate-AMP ligase. Cat No: EXWM-3269. | |
| 23S rRNA pseudouridine1911/1915/1917 synthase | Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines. These nucleotides are located in the functionally important helix-loop 69 of 23S rRNA. Group: Enzymes. Synonyms: RluD; pseudouridine synthase RluD. Enzyme Commission Number: EC 5.4.99.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5563; 23S rRNA pseudouridine1911/1915/1917 synthase; EC 5.4.99.23; RluD; pseudouridine synthase RluD. Cat No: EXWM-5563. | |
| 23S rRNA pseudouridine2457 synthase | The enzyme modifies uridine2457 in a stem of 23S RNA in Escherichia coli. Group: Enzymes. Synonyms: RluE; YmfC. Enzyme Commission Number: EC 5.4.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5560; 23S rRNA pseudouridine2457 synthase; EC 5.4.99.20; RluE; YmfC. Cat No: EXWM-5560. | |
| 23S rRNA pseudouridine2604 synthase | The enzyme is not completely specific for uridine2604 and can, to a small extent, also react with uridine2605. Group: Enzymes. Synonyms: RluF; YjbC. Enzyme Commission Number: EC 5.4.99.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5561; 23S rRNA pseudouridine2604 synthase; EC 5.4.99.21; RluF; YjbC. Cat No: EXWM-5561. | |
| 23S rRNA pseudouridine2605 synthase | Pseudouridine synthase RluB converts uridine2605 of 23S rRNA to pseudouridine. Group: Enzymes. Synonyms: RluB; YciL. Enzyme Commission Number: EC 5.4.99.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5562; 23S rRNA pseudouridine2605 synthase; EC 5.4.99.22; RluB; YciL. Cat No: EXWM-5562. | |
| 23S rRNA pseudouridine746 synthase | RluA is the sole protein responsible for the in vivo formation of 23S RNA pseudouridine746. The dual-specificity enzyme also catalyses the formation of uridine32 in tRNA. cf. EC 5.4.99.28 (tRNA pseudouridine32 synthase). Group: Enzymes. Synonyms: RluA (ambiguous); 23S RNA PSI746 synthase; 23S rRNA pseudouridine synthase; pseudouridine synthase RluA (ambiguous). Enzyme Commission Number: EC 5.4.99.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5569; 23S rRNA pseudouridine746 synthase; EC 5.4.99.29; RluA (ambiguous); 23S RNA PSI746 synthase; 23S rRNA pseudouridine synthase; pseudouridine synthase RluA (ambiguous). Cat No: EXWM-5569. | |
| 23S rRNA pseudouridine955/2504/2580 synthase | The enzyme converts uridines at position 955, 2504 and 2580 of 23S rRNA to pseudouridines. Group: Enzymes. Synonyms: RluC; pseudouridine synthase RluC. Enzyme Commission Number: EC 5.4.99.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5564; 23S rRNA pseudouridine955/2504/2580 synthase; EC 5.4.99.24; RluC; pseudouridine synthase RluC. Cat No: EXWM-5564. | |
| 2,4,6-trihydroxybenzophenone synthase | Involved in the biosynthesis of plant xanthones. The enzyme from the plant Hypericum androsaemum L can use 3-hydroxybenzoyl-CoA instead of benzoyl-CoA, but with lower activity (cf. EC 2.3.1.151, 2,3',4,6-tetrahydroxybenzophenone synthase). Group: Enzymes. Synonyms: benzophenone synthase (ambiguous); BPS (ambiguous). Enzyme Commission Number: EC 2.3.1.220. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2167; 2,4,6-trihydroxybenzophenone synthase; EC 2.3.1.220; benzophenone synthase (ambiguous); BPS (ambiguous). Cat No: EXWM-2167. | |
| 2'-5' oligoadenylate synthase | The enzyme is activated by binding to double-stranded RNA. The resulting product binds to and activates RNase L, which subsequently degrades the RNA. Oligoadenylates of chain lengths 2, 4 and 5 are also produced. The dimer does not have any known biological activity. Group: Enzymes. Synonyms: OAS. Enzyme Commission Number: EC 2.7.7.84. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3297; 2'-5' oligoadenylate synthase; EC 2.7.7.84; OAS. Cat No: EXWM-3297. | |
| 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase | The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme can also catalyse the reaction of EC 4.1.2.13, fructose-bisphosphate aldolase. Group: Enzymes. Synonyms: ADH synthase; ADHS; MJ0400 (gene name). Enzyme Commission Number: EC 2.2.1.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2026; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; EC 2.2.1.10; ADH synthase; ADHS; MJ0400 (gene name). Cat No: EXWM-2026. | |
| 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase | Part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus. Group: Enzymes. Synonyms: griI (gene name). Enzyme Commission Number: EC 4.1.2.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4893; 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase; EC 4.1.2.56; griI (gene name). Cat No: EXWM-4893. | |
| 2-amino-4-deoxychorismate synthase | Requires Mg2+. The reaction occurs in the reverse direction to that shown above. In contrast to most anthranilate-synthase I (ASI) homologues, this enzyme is not inhibited by tryptophan. In Streptomyces globisporus, the sequential action of this enzyme and EC 1.3.99.24, 2-amino-4-deoxychorismate dehydrogenase, leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027.In certain Pseudomonads the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity. Group: Enzymes. Synonyms: ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Enzyme Commission Number: EC 2.6.1.86. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2927; 2-amino-4-deoxychorismate synthase; EC 2.6.1.86; ADIC synthase; 2-amino-2-deoxyisochorismate synthase;SgcD. Cat No: EXWM-2927. | |
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | The enzyme from Escherichia coli requires Mg2+ or Mn2+. Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis (for diagram, click here). Group: Enzymes. Synonyms: MECDP-synthase; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.12. CAS No. 287480-92-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5349; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; EC 4.6.1.12; 287480-92-6; MECDP-synthase; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing). Cat No: EXWM-5349. | |
| 2-deoxy-scyllo-inosose synthase | Requires Co2+. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Requires an NAD+ cofactor, which is transiently reduced during the reaction. The enzyme from the bacterium Bacillus circulans forms a complex with the glutamine amidotransferase subunit of pyridoxal 5'-phosphate synthase (EC 4.3.3.6), which appears to stabilize the complex. Group: Enzymes. Synonyms: btrC (gene name); neoC (gene name); kanC (gene name). Enzyme Commission Number: EC 4.2.3.124. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5137; 2-deoxy-scyllo-inosose synthase; EC 4.2.3.124; btrC (gene name); neoC (gene name); kanC (gene name). Cat No: EXWM-5137. | |
| (2E,6E)-farnesyl diphosphate synthase | Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. The enzyme will not accept larger prenyl diphosphates as efficient donors. Group: Enzymes. Synonyms: farnesyl-diphosphate synthase; geranyl transferase I; prenyltransferase; farnesyl pyrophosphate synthetase; farnesylpyrophosphate synthetase; geranyltranstransferase. Enzyme Commission Number: EC 2.5.1.10. CAS No. 37277-79-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2715; (2E,6E)-farnesyl diphosphate synthase; EC 2.5.1.10; 37277-79-5; farnesyl-diphosphate synthase; geranyl transferase I; prenyltransferase; farnesyl pyrophosphate synthetase; farnesylpyrophosphate synthetase; geranyltranstransferase. Cat No: EXWM-2715. | |
| 2-epi-5-epi-valiolone synthase | The enzyme is highly specific for α-D-sedoheptulopyranose 7-phosphate. It requires a divalent metal ion (Zn2+ or Co2+) and an NAD+ cofactor, which is transiently reduced during the reaction. The enzyme is involved in the biosynthesis of C7N-aminocyclitol natural products, such as the valienamine moiety of the antidiabetic drug acarbose and the crop protectant validamycin A. cf. EC 4.2.3.155, 2-epi-valiolone synthase and EC 4.2.3.154, demethyl-4-deoxygadusol synthase. Group: Enzymes. Synonyms: AcbC; ValA; CetA; SalQ; C7-cyclitol synthase. Enzyme Commission Number: EC 4.2.3.152. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5167; 2-epi-5-epi-valiolone synthase; EC 4.2.3.152; AcbC; ValA; CetA; SalQ; C7-cyclitol synthase. Cat No: EXWM-5167. | |
| 2-epi-valiolone synthase | The enzyme, characterized from the bacteria Actinosynnema mirum and Stigmatella aurantiaca DW4/3-1, produces 2-epi-valiolone, which is believed to function as a precursor in aminocyclitol biosynthesis. It requires a divalent metal ion (Zn2+ or Co2+) and an NAD+ cofactor, which is transiently reduced during the reaction. cf. EC 4.2.3.152, 2-epi-5-epi-valiolone synthase and EC 4.2.3.154, demethyl-4-deoxygadusol synthase. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.155. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5170; 2-epi-valiolone synthase; EC 4.2.3.155. Cat No: EXWM-5170. | |
| 2-ethylmalate synthase | Also acts on (R)-2-(n-propyl)-malate. Formerly wrongly included with EC 2.3.3.7 3-ethylmalate synthase. Group: Enzymes. Synonyms: (R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating); 2-ethylmalate-3-hydroxybutanedioate synthase; propylmalate synthase; propylmalic synthase. Enzyme Commission Number: EC 2.3.3.6. CAS No. 9024-1-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2322; 2-ethylmalate synthase; EC 2.3.3.6; 9024-01-5; (R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating); 2-ethylmalate-3-hydroxybutanedioate synthase; propylmalate synthase; propylmalic synthase. Cat No: EXWM-2322. | |
| 2-heptyl-3-hydroxy-4(1H)-quinolone synthase | The enzyme from the bacterium Pseudomonas aeruginosa catalyses the terminal step in biosynthesis of the signal molecule 2-heptyl-3,4-dihydroxyquinoline that plays a role in regulation of virulence genes. Group: Enzymes. Synonyms: PqsH; 2-heptyl-3,4-dihydroxyquinoline synthase. Enzyme Commission Number: EC 1.14.13.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0781; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase; EC 1.14.13.182; PqsH; 2-heptyl-3,4-dihydroxyquinoline synthase. Cat No: EXWM-0781. | |
| 2-heptyl-4(1H)-quinolone synthase | The enzyme from the Gram-negative bacterium Pseudomonas aeruginosa is involved in the biosynthesis of 2-heptyl-4-hydroxyquinoline and 2,4-dihydroxyquinoline. 2-Heptyl-4-hydroxyquinoline is a signal molecule, that is involved in regulation of virulence factor production and biofilm formation. The enzyme shows a broad specificity and is involved in the synthesis of a wide array of additional 2-alkyl-4(1H)-quinolones synthesized by the organism. Group: Enzymes. Enzyme Commission Number: EC 2.3.1.230. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2178; 2-heptyl-4(1H)-quinolone synthase; EC 2.3.1.230. Cat No: EXWM-2178. | |
| 2-hydroxy-3-oxoadipate synthase | The bacterial enzyme requires thiamine diphosphate. The product decarboxylates to 5-hydroxy-4-oxopentanoate. The enzyme can decarboxylate 2-oxoglutarate. Acetaldehyde can replace glyoxylate. Group: Enzymes. Synonyms: 2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating); α-ketoglutaric-glyoxylic carboligase; oxoglutarate: glyoxylate carboligase. Enzyme Commission Number: EC 2.2.1.5. CAS No. 9054-72-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2032; 2-hydroxy-3-oxoadipate synthase; EC 2.2.1.5; 9054-72-2; 2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating); α-ketoglutaric-glyoxylic carboligase; oxoglutarate: glyoxylate carboligase. Cat No: EXWM-2032. | |
| 2-hydroxyglutarate synthase | This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. This enzyme participates in c5-branched dibasic acid metabolism. Group: Enzymes. Synonyms: 2-hydroxyglutaratic synthetase; 2-hydroxyglutaric synthetase; α-hydroxyglutarate synthase; hydroxyglutarate synthase; 2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating). Enzyme Commission Number: EC 2.3.3.11. CAS No. 9024-2-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2312; 2-hydroxyglutarate synthase; EC 2.3.3.11; 9024-02-6; 2-hydroxyglutaratic synthetase; 2-hydroxyglutaric synthetase; α-hydroxyglutarate synthase; hydroxyglutarate synthase; 2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating). Cat No: EXWM-2312. | |
| 2-hydroxyisoflavanone synthase | Requires cytochrome P-450. The reaction involves the migration of the 2-phenyl group of the flavanone to the 3-position of the isoflavanone. The 2-hydroxyl group is derived from the oxygen molecule. EC 4.2.1.105, 2-hydroxyisoflavanone dehydratase, acts on the products with loss of water and formation of genistein and daidzein, respectively. Group: Enzymes. Synonyms: CYP93C; IFS; isoflavonoid synthase. Enzyme Commission Number: EC 1.14.13.136. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0735; 2-hydroxyisoflavanone synthase; EC 1.14.13.136; CYP93C; IFS; isoflavonoid synthase. Cat No: EXWM-0735. | |
| 2-iminoacetate synthase | Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the S-adenosyl-L-methionine to produce methionine and a 5-deoxyadenosin-5-yl radical that is crucial for the conversion of the substrate. The reductant is assumed to be NADPH, which is provided by a flavoprotein:NADPH oxidoreductase system. Part of the pathway for thiamine biosynthesis. Group: Enzymes. Synonyms: thiH (gene name). Enzyme Commission Number: EC 4.1.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4932; 2-iminoacetate synthase; EC 4.1.99.19; thiH (gene name). Cat No: EXWM-4932. | |
| 2-isopropylmalate synthase | Requires K+. Group: Enzymes. Synonyms: 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating); α-isopropylmalate synthetase; α-isopropylmalate synthase; α-isopropylmalic synthetase; isopropylmalate synthase; isopropylmalate synthetase. Enzyme Commission Number: EC 2.3.3.13. CAS No. 9030-98-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2314; 2-isopropylmalate synthase; EC 2.3.3.13; 9030-98-2; 3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating); α-isopropylmalate synthetase; α-isopropylmalate synthase; α-isopropylmalic synthetase; isopropylmalate synthase; isopropylmalate synthetase. Cat No: EXWM-2314. | |
| 2-methylbutanoate polyketide synthase | This polyketide synthase enzyme forms the (S)-2-methylbutanoate side chain during lovastatin biosynthesis by the filamentous fungus Aspergillus terreus. The overall reaction comprises a single condensation reaction followed by α-methylation, β-ketoreduction, dehydration, and α,β enoyl reduction. Group: Enzymes. Synonyms: LovF. Enzyme Commission Number: EC 2.3.1.244. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2193; 2-methylbutanoate polyketide synthase; EC 2.3.1.244; LovF. Cat No: EXWM-2193. | |
| 2-methylcitrate synthase | The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA. The relative rate of condensation of acetyl-CoA and oxaloacetate is 140% of that of propanoyl-CoA and oxaloacetate, but the enzyme is distinct from EC 2.3.3.1, citrate (Si)-synthase. Oxaloacetate cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate. Group: Enzymes. Synonyms: 2-methylcitrate oxaloacetate-lyase; MCS; methylcitrate synthase; methylcitrate synthetase. Enzyme Commission Number: EC 2.3.3.5. CAS No. 57827-78-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2321; 2-methylcitrate synthase; EC 2.3.3.5; 57827-78-8; 2-methylcitrate oxaloacetate-lyase; MCS; methylcitrate synthase; methylcitrate synthetase. Cat No: EXWM-2321. | |
| 2-methylisoborneol synthase | The product, 2-methylisoborneol, is a characteristc odiferous compound with a musty smell produced by soil microorganisms. Group: Enzymes. Synonyms: sco7700; 2-MIB cyclase; MIB synthase; MIBS. Enzyme Commission Number: EC 4.2.3.118. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5130; 2-methylisoborneol synthase; EC 4.2.3.118; sco7700; 2-MIB cyclase; MIB synthase; MIBS. Cat No: EXWM-5130. | |
| 2-oxoglutarate synthase | The enzyme contains thiamine diphosphate and two [4Fe-4S] clusters. Highly specific for 2-oxoglutarate. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.1, pyruvate synthase and EC 1.2.7.7, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin). Group: Enzymes. Synonyms: 2-ketoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin oxidoreductase; KGOR; 2-oxoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating). Enzyme Commission Number: EC 1.2.7.3. CAS No. 37251-05-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1226; 2-oxoglutarate synthase; EC 1.2.7.3; 37251-05-1; 2-ketoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin oxidoreductase; KGOR; 2-oxoglutarate ferredoxin oxidoreductase; 2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating). Cat No: EXWM-1226. | |
| 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | Requires Mg2+ for maximal activity. This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the products of the reaction were (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC), pyruvate and CO2 but it is now known that two separate enzymes are involved: this enzyme and EC 4.2.99.20, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. Under basic conditions, the product can spontaneously lose pyruvate to form SHCHC. Group: Enzymes. Synonyms: SEPHCHC synthase; MenD. Enzyme Commission Number: EC 2.2.1.9. CAS No. 1112282-73-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2036; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase; EC 2.2.1.9; 1112282-73-1; SEPHCHC synthase; MenD. Cat No: EXWM-2036. | |
| 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the reactions carried out by this enzyme and EC 2.2.1.9, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, were carried out by a single enzyme but this has since been disproved. Group: Enzymes. Synonyms: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Enzyme Commission Number: EC 4.2.99.20. CAS No. 122007-88-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5266; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; EC 4.2.99.20; 122007-88-9; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase; 6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase; SHCHC synthase; MenH; YfbB. Cat No: EXWM-5266. | |
| (2Z,6E)-farnesyl diphosphate synthase | Requires Mg2+ or Mn2+ for activity. The product of this reaction is an intermediate in the synthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan. Neryl diphosphate can also act as substrate. Group: Enzymes. Synonyms: (Z)-farnesyl diphosphate synthase; Z-farnesyl diphosphate synthase. Enzyme Commission Number: EC 2.5.1.68. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2805; (2Z,6E)-farnesyl diphosphate synthase; EC 2.5.1.68; (Z)-farnesyl diphosphate synthase; Z-farnesyl diphosphate synthase. Cat No: EXWM-2805. | |
| (2Z,6Z)-farnesyl diphosphate synthase | This enzyme, originally characterized from wild tomato, specifically forms (2Z,6Z)-farnesyl diphosphate via neryl diphosphate and isopentenyl diphosphate. In wild tomato it is involved in the biosynthesis of several sesquiterpenes. See also EC 2.5.1.68 [(2Z,6E)-farnesyl diphosphate synthase] and EC 2.5.1.10 [(2E,6E)-farnesyl diphosphate synthase]. Group: Enzymes. Synonyms: cis,cis-farnesyl diphosphate synthase; Z,Z-FPP synthase; zFPS; Z,Z-farnesyl pyrophosphate synthase. Enzyme Commission Number: EC 2.5.1.92. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2831; (2Z,6Z)-farnesyl diphosphate synthase; EC 2.5.1.92; cis,cis-farnesyl diphosphate synthase; Z,Z-FPP synthase; zFPS; Z,Z-farnesyl pyrophosphate synthase. Cat No: EXWM-2831. | |
| 3,4-dihydroxy-2-butanone-4-phosphate synthase | Requires a divalent cation, preferably Mg2+, for activity. The reaction involves an intramolecular skeletal rearrangement, with the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4 being broken, C-4 being removed as formate and reconnection of C-3 and C-5. The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one 4-phosphate) is an intermediate in the biosynthesis of riboflavin. Group: Enzymes. Synonyms: DHBP synthase; L-3,4-dihydroxybutan-2-one-4-phosphate synthase. Enzyme Commission Number: EC 4.1.99.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4927; 3,4-dihydroxy-2-butanone-4-phosphate synthase; EC 4.1.99.12; DHBP synthase; L-3,4-dihydroxybutan-2-one-4-phosphate synthase. Cat No: EXWM-4927. | |
| 3,5,7-trioxododecanoyl-CoA synthase | A polyketide synthase catalysing the first committed step in the cannabinoids biosynthetic pathway of the plant Cannabis sativa. The enzyme was previously thought to also function as a cyclase, but the cyclization is now known to be catalysed by EC 4.4.1.26, olivetolic acid cyclase. Group: Enzymes. Synonyms: TKS (ambiguous); olivetol synthase (incorrect). Enzyme Commission Number: EC 2.3.1.206. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2151; 3,5,7-trioxododecanoyl-CoA synthase; EC 2.3.1.206; TKS (ambiguous); olivetol synthase (incorrect). Cat No: EXWM-2151. | |
| 3,5-dihydroxybiphenyl synthase | A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-Hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 4-hydroxycoumarin (cf. EC 2.3.1.208, 4-hydroxycoumarin synthase). This enzyme uses the same starter substrate as EC 2.3.1.151, benzophenone synthase. Group: Enzymes. Synonyms: BIS1; biphenyl synthase (ambiguous). Enzyme Commission Number: EC 2.3.1.177. CAS No. 1217551-24-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2118; 3,5-dihydroxybiphenyl synthase; EC 2.3.1.177; 1217551-24-0; BIS1; biphenyl synthase (ambiguous). Cat No: EXWM-2118. | |
| 3,5-dihydroxyphenylacetyl-CoA synthase | The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the nonproteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin. Group: Enzymes. Synonyms: DpgA. Enzyme Commission Number: EC 2.3.1.246. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2195; 3,5-dihydroxyphenylacetyl-CoA synthase; EC 2.3.1.246; DpgA. Cat No: EXWM-2195. | |
| 3-acetyloctanal synthase | Requires thiamine diphosphate. The enzyme, characterized from the bacterium Serratia marcescens, participates in the biosynthesis of the antibiotic prodigiosin. The enzyme decarboxylates pyruvate, followed by attack of the resulting two-carbon fragment on (E)-oct-2-enal, resulting in a Stetter reaction. In vitro the enzyme can act on a number of α,β-unsaturated carbonyl compounds, including aldehydes and ketones, and can catalyse both 1-2 and 1-4 carboligations depending on the substrate. Group: Enzymes. Synonyms: pigD (gene name). Enzyme Commission Number: EC 2.2.1.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2028; 3-acetyloctanal synthase; EC 2.2.1.12; pigD (gene name). Cat No: EXWM-2028. | |
| 3-amino-4-hydroxybenzoate synthase | Requires Mn2+ for maximum activity. The reaction is suggested to take place in several steps. Schiff base formation, double bond migration and dephosphorylation followed by ring opening and closing to form a pyrrolidine ring, and finally dehydration to form the product 3-amino-4-hydroxybenzoate. In the bacterium Streptomyces griseus the enzyme is involved in biosynthesis of grixazone, a yellow pigment that contains a phenoxazinone chromophore. Group: Enzymes. Synonyms: 3,4-AHBA synthase; griH (gene name). Enzyme Commission Number: EC 4.1.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4934; 3-amino-4-hydroxybenzoate synthase; EC 4.1.99.20; 3,4-AHBA synthase; griH (gene name). Cat No: EXWM-4934. | |
| 3-amino-5-hydroxybenzoate synthase | A pyridoxal 5'-phosphate enzyme. The enzyme from the bacterium Amycolatopsis mediterranei participates in the pathway for rifamycin B biosynthesis. The enzyme also functions as a transaminase earlier in the pathway, producing UDP-α-D-kanosamine. Group: Enzymes. Synonyms: AHBA synthase; rifK (gene name). Enzyme Commission Number: EC 4.2.1.144. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4985; 3-amino-5-hydroxybenzoate synthase; EC 4.2.1.144; AHBA synthase; rifK (gene name). Cat No: EXWM-4985. | |
| 3-dehydroquinate synthase | Requires Co2+ and bound NAD+. The hydrogen atoms on C-7 of the substrate are retained on C-2 of the product. Group: Enzymes. Synonyms: 5-dehydroquinate synthase; 5-dehydroquinic acid synthetase; dehydroquinate synthase; 3-dehydroquinate synthetase; 3-deoxy-arabino-heptulosonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming). Enzyme Commission Number: EC 4.2.3.4. CAS No. 37211-77-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5198; 3-dehydroquinate synthase; EC 4.2.3.4; 37211-77-1; 5-dehydroquinate synthase; 5-dehydroquinic acid synthetase; dehydroquinate synthase; 3-dehydroquinate synthetase; 3-deoxy-arabino-heptulosonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming). Cat No: EXWM-5198. | |
| 3-dehydroquinate synthase II | The enzyme, which was isolated from the archaeon Methanocaldococcus jannaschii, plays a key role in an alternative pathway for the biosynthesis of 3-dehydroquinate (DHQ), an intermediate of the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme catalyses a two-step reaction - an oxidative deamination, followed by cyclization. Group: Enzymes. Synonyms: DHQ synthase II; MJ1249 (gene name); aroB' (gene name). Enzyme Commission Number: EC 1.4.1.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1457; 3-dehydroquinate synthase II; EC 1.4.1.24; DHQ synthase II; MJ1249 (gene name); aroB' (gene name). Cat No: EXWM-1457. | |
| 3-deoxy-7-phosphoheptulonate synthase | 3-Deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) synthase (EC 2.5.1.54) is the first enzyme in a series of metabolic reactions known as the shikimate pathway, which is responsible for the biosynthesis of the amino acids phenylalanine, tyrosine, and tryptophan. Group: Enzymes. Synonyms: 2-dehydro-3-deoxy-phosphoheptonate aldolase; 2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase; 3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase; 3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase; 7-p. Enzyme Commission Number: EC 2.5.1.54. CAS No. 9026-94-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2791; 3-deoxy-7-phosphoheptulonate synthase; EC 2.5.1.54; 9026-94-2; 2-dehydro-3-deoxy-phosphoheptonate aldolase; 2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase; 3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase; 3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase; 7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating); 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating); D-erythrose-4-phosphate-lyase; D-ery | |
| 3-deoxy-8-phosphooctulonate synthase | This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. This enzyme participates in lipopolysaccharide biosynthesis. Group: Enzymes. Synonyms: 2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating); 2-dehydro-3-deoxy-phosphooctonate aldolase; 2-keto-3-deoxy-8-phosphooctonic synthetase; 3-deoxy-D-manno-octulosonate-8-phosphate synthase; 3-deoxy-D-mannooctulosonate-8-phosphate synthetase; 3-deoxyoctulosonic 8-phosphate synthetase; KDOP synthase; phospho-2-keto-3-deoxyoctonate aldolase. Enzyme Commission Number: EC 2.5.1.55. CAS No. 9026-96-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2792; 3-deoxy-8-phosphooctulonate synthase; EC 2.5.1.55; 9026-96-4; 2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating); 2-dehydro-3-deoxy-phosphooctonate aldolase; 2-keto-3-deoxy-8-phosphooctonic synthetase; 3-deoxy-D-manno-octulosonate-8-phosphate synthase; 3-deoxy-D-mannooctulosonate-8-phosphate synthetase; 3-deoxyoctulosonic 8-phosphate synthetase; KDOP synthase; phospho-2-keto-3-deoxyoctonate aldolase. Cat No: EXWM-2792. | |
| 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase | The enzyme participates in the biosynthesis of the sialic acid 3-deoxy-D-glycero-D-galacto-nononate (KDN). The human sialic acid synthase (EC 2.5.1.57) is also able to catalyse the reaction. KDN is abundant in extracellular glycoconjugates of lower vertebrates such as fish and amphibians, but is also found in the capsular polysaccharides of bacteria that belong to the Bacteroides genus. Group: Enzymes. Synonyms: 2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid synthase; KDN 9-P synthase. Enzyme Commission Number: EC 2.5.1.132. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2748; 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase; EC 2.5.1.132; 2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid synthase; KDN 9-P synthase. Cat No: EXWM-2748. | |
| 3-ethylmalate synthase | This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. This enzyme participates in glyoxylate and dicarboxylate metabolism. Group: Enzymes. Synonyms: 2-ethyl-3-hydroxybutanedioate synthase; 3-ethylmalate glyoxylate-lyase (CoA-butanoylating). Enzyme Commission Number: EC 2.3.3.7. CAS No. 9024-1-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2323; 3-ethylmalate synthase; EC 2.3.3.7; 9024-01-5; 2-ethyl-3-hydroxybutanedioate synthase; 3-ethylmalate glyoxylate-lyase (CoA-butanoylating). Cat No: EXWM-2323. | |
| 3-hexulose-6-phosphate synthase | Requires Mg2+ or Mn2+ for maximal activity. The enzyme is specific for D-ribulose 5-phosphate as substrate as ribose 5-phosphate, xylulose 5-phosphate, allulose 6-phosphate and fructose 6-phosphate cannot act as substrate. In addition to formaldehyde, the enzyme can also use glycolaldehyde and methylglyoxal. This enzyme, along with EC 5.3.1.27, 6-phospho-3-hexuloisomerase, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds. The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyses the reactions of this enzyme and EC 5.3.1.27, 6-phospho-3-hexuloisomerase. This enzyme is a member of the orotidine 5'-monophosphate decarboxylase (OMPDC) suprafamily. Group: Enzymes. Synonyms: D-arabino-3-hexulose 6-phosphate formaldehyde-lyase; 3-hexulosephosphate synthase; 3-hexulose phosphate synthase; HPS. Enzyme Commission Number: EC 4.1.2.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4879; 3-hexulose-6-phosphate synthase; EC 4.1.2.43; D-arabino-3-hexulose 6-phosphate formaldehyde-lyase; 3-hexulosephosphate synthase; 3-hexulose phosphate synthase; HPS. Cat No: EXWM-4879. | |
| 3-hydroxybenzoate synthase | The enzyme, found in several bacterial species is involved in biosynthesis of secondary products. The enzyme from the bacterium Xanthomonas campestris pv. campestris also has the activity of EC 4.1.3.40, chorismate lyase. Group: Enzymes. Synonyms: chorismatase/3-hydroxybenzoate synthase; hyg5 (gene name); bra8 (gene name); XanB2. Enzyme Commission Number: EC 4.1.3.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4922; 3-hydroxybenzoate synthase; EC 4.1.3.45; chorismatase/3-hydroxybenzoate synthase; hyg5 (gene name); bra8 (gene name); XanB2. Cat No: EXWM-4922. | |
| 3-hydroxypropionyl-CoA synthase | Catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea.The enzymes from Metallosphaera sedula and Sulfolobus tokodaii can also use propionate, acrylate, acetate, and butanoate as substrates, and are thus different from EC 6.2.1.17 (propionate-CoA ligase), which does not accept acetate or butanoate. Group: Enzymes. Synonyms: 3-hydroxypropionyl-CoA synthetase (AMP-forming); 3-hydroxypropionate-CoA ligase. Enzyme Commission Number: EC 6.2.1.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5694; 3-hydroxypropionyl-CoA synthase; EC 6.2.1.36; 3-hydroxypropionyl-CoA synthetase (AMP-forming); 3-hydroxypropionate-CoA ligase. Cat No: EXWM-5694. | |
| 3-propylmalate synthase | This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. This enzyme participates in glyoxylate and dicarboxylate metabolism. Group: Enzymes. Synonyms: 3-(n-propyl)-malate synthase; 3-propylmalate glyoxylate-lyase (CoA-pentanoylating); β-n-propylmalate synthase; n-propylmalate synthase. Enzyme Commission Number: EC 2.3.3.12. CAS No. 37290-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2313; 3-propylmalate synthase; EC 2.3.3.12; 37290-62-3; 3-(n-propyl)-malate synthase; 3-propylmalate glyoxylate-lyase (CoA-pentanoylating); β-n-propylmalate synthase; n-propylmalate synthase. Cat No: EXWM-2313. | |
| (3R,6E)-nerolidol synthase | The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores. Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants. Group: Enzymes. Synonyms: terpene synthase 1. Enzyme Commission Number: EC 4.2.3.49. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5208; (3R,6E)-nerolidol synthase; EC 4.2.3.49; terpene synthase 1. Cat No: EXWM-5208. | |
| (3S,6E)-nerolidol synthase | The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores. Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants. Group: Enzymes. Synonyms: (E)-nerolidol synthase; nerolidol synthase; (3S)-(E)-nerolidol synthase; FaNES1. Enzyme Commission Number: EC 4.2.3.48. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5207; (3S,6E)-nerolidol synthase; EC 4.2.3.48; (E)-nerolidol synthase; nerolidol synthase; (3S)-(E)-nerolidol synthase; FaNES1. Cat No: EXWM-5207. | |
| (4-{4-[2- (γ -L-glutamylamino) ethyl]phenoxymethyl}furan-2-yl) methanamine synthase | The enzyme, isolated from the archaeon Methanocaldococcus jannaschii, participates in the biosynthesis of the methanofuran cofactor. Group: Enzymes. Synonyms: MfnF. Enzyme Commission Number: EC 2.5.1.131. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2747; (4-{4-[2- (γ -L-glutamylamino) ethyl]phenoxymethyl}furan-2-yl) methanamine synthase; EC 2.5.1.131; MfnF. Cat No: EXWM-2747. | |
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