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| Product | Description | |
|---|---|---|
| T-5224 | T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation. Accumulating evidence supports that AP-1 plays an important role in several severe disorders including cancer, fibrosis, and organ injury, as well as inflammatory disorders such as asthma, psoriasis, and rheumatoid arthritis. Synonyms: T5224; T 5224. Grades: >98%. CAS No. 530141-72-1. Molecular formula: C29H27NO8. Mole weight: 517.53. |  |
| T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 530141-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12270. |  |
| 2-Hydroxy-2-oxoacetate;1-(7-hydroxy-2-oxo-3,4-dihydroquinolin-1-yl)propan-2-yl-methyl-(2-phenylethyl)azanium | 2-Hydroxy-2-oxoacetate;1-(7-hydroxy-2-oxo-3,4-dihydroquinolin-1-yl)propan-2-yl-methyl-(2-phenylethyl)azanium. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,4-Dihydro-7-hydroxy-1-(2-(methylphenethylamino)propyl)carbostyril oxalate, CARBOSTYRIL, 3,4-DIHYDRO-7-HYDROXY-1-(2-(METHYLPHENETHYLAMINO)PROPYL)-, OXALATE, AC1L1OGQ, AC1Q229C, LS-52249, 101173-03-9, 2-hydroxy-2-oxoacetate; 1-(7-hydroxy-2-oxo-3,4-dihydroquinolin-1-yl)propan-2-yl-methyl-phenethylazanium, 7-hydroxy-1-{2-[methyl(2-phenylethyl)amino]propyl}-3,4-dihydroquinolin-2(1h)-one ethanedioate(salt). Product Category: Heterocyclic Organic Compound. CAS No. 101173-03-9. Molecular formula: C23H28N2O6. Mole weight: 428.478 g/mol. Purity: 0.96. IUPACName: 2-hydroxy-2-oxoacetate;1-(7-hydroxy-2-oxo-3,4-dihydroquinolin-1-yl)propan-2-yl-methyl-(2-phenylethyl)azanium. Canonical SMILES: CC(CN1C(=O)CCC2=C1C=C(C=C2)O)[NH+](C)CCC3=CC=CC=C3.C(=O)(C(=O)[O-])O. Product ID: ACM101173039. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (+)-cubenene synthase | Requires Mg2+. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.63. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5224; (+)-cubenene synthase; EC 4.2.3.63. Cat No: EXWM-5224. |  |
| Diethyl-[2-(2-oxo-3,4-dihydroquinolin-1-yl)ethyl]azanium;2,4,6-trinitrophenolate | Diethyl-[2-(2-oxo-3,4-dihydroquinolin-1-yl)ethyl]azanium;2,4,6-trinitrophenolate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,4-Dihydro-1-(2-(diethylamino)ethyl)carbostyril picrate, CARBOSTYRIL, 3,4-DIHYDRO-1-(2-(DIETHYLAMINO)ETHYL)-, PICRATE, AC1Q1YIE, AC1L1OS0, LS-52247, diethyl-[2-(2-oxo-3,4-dihydroquinolin-1-yl)ethyl]azanium; 2,4,6-trinitrophenolate, n,n-diethyl-2-(2-oxo-3,4-dihydroquinolin-1(2h)-yl)ethanaminium 2,4,6-trinitrophenolate, 101418-17-1. Product Category: Heterocyclic Organic Compound. CAS No. 101418-17-1. Molecular formula: C21H25N5O8. Mole weight: 475.452 g/mol. Purity: 0.96. IUPACName: diethyl-[2-(2-oxo-3,4-dihydroquinolin-1-yl)ethyl]azanium;2,4,6-trinitrophenolate. Canonical SMILES: CC[NH+](CC)CCN1C(=O)CCC2=CC=CC=C21.C1=C(C=C(C(=C1[N+](=O)[O-])[O-])[N+](=O)[O-])[N+](=O)[O-]. Product ID: ACM101418171. Alfa Chemistry ISO 9001:2015 Certified. | |
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