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Tacedinaline Tacedinaline is a histone deacetylase (HDAC) inhibitor. It can promote hepatic differentiation in hPSCs. Synonyms: CI 994; CI-994; Acetyldinaline; 4-acetamido-N-(2-aminophenyl)benzamide. Grades: >98%. CAS No. 112522-64-2. Molecular formula: C15H15N3O2. Mole weight: 269.304. BOC Sciences 11
Tacedinaline Tacedinaline is a histone deacetylase (HDAC) inhibitor. Tacedinaline is an anti-cancer agent as HDAC inhibitors block angiogenesis, arrest cell growth, and lead to differentiation and apoptosis in tumor cells. Studies show Tacedinaline to be effective against acute myeloid leukemia in vitro and in vivo when used in combination with conventional anti-cancer agents. Group: Biochemicals. Alternative Names: 4-(Acetylamino)-N-(2-aminophenyl)benzamide; Acetyldinaline; CI 994; Goe 5549; PD 123654. Grades: Highly Purified. CAS No. 112522-64-2. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 3
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Tacedinaline Tacedinaline (N-acetyldinaline) is an inhibitor of the histone deacetylase ( HDAC ) with IC 50 s of 0.9, 0.9, 1.2 μM for recombinant HDAC 1, 2 and 3 respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-acetyldinaline; CI-994; Goe-5549. CAS No. 112522-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50934. MedChemExpress MCE
Tacedinaline (CI-994) Tacedinaline, also known as CI-944 and PD123654, is a n orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CI994, CI-994, CI 994, PD123654, PD-123654, PD 123654, Tacedinaline, acetyldinaline. Product Category: Others. Appearance: Off-white solid powder. CAS No. 112522-64-2. Molecular formula: C15H15N3O2. Mole weight: 269.3. Purity: >98%. IUPACName: 4-acetamido-N-(2-aminophenyl)benzamide. Canonical SMILES: O=C(NC1=CC=CC=C1N)C2=CC=C(NC(C)=O)C=C2. Product ID: ACM112522642. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
CI-994, Free Base (4-(Acetylamino)-N-(2-aminophenyl)benzamide, Acetyldinaline, 5'-Deoxy-5-fluoro-N- ( (pentyloxy) carbonyl) cytidine, Goe 5549, Gö 5549, PD 123654, Tacedinaline) CI-994 is a histone deacetylase (HDAC) inhibitor and induces histone hyperacetylation in living cells. CI-994 inhibited HDAC-1 and HDAC-2 but not the prototypical histone acetyltransferase GCN5. Group: Biochemicals. Grades: Highly Purified. CAS No. 112522-64-2. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 1
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