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| Product | Description | |
|---|---|---|
| Tacrolimus monohydrate | Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate. CAS No. 109581-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13756A. |  |
| Tacrolimus monohydrate | Tacrolimus monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 109581-93-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C44H69NO12·H2O. US Biological Life Sciences. |  Worldwide |
| Tacrolimus EP Impurity C | Tacrolimus EP Impurity C is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 12, 18-trimethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; 10-Desmethyl tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 12, 18-trimethyl-8-(2-propen-1-yl)-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; Tacrolimus monohydrate EP impurity C; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Allyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl]-14, 16-dimethoxy-4, 12, 18-trimethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone; Desmethyl tacrolimus. Grades: ≥95%. Molecular formula: C43H67NO12. Mole weight: 789.99. |  |
| Tacrolimus EP Impurity D | Tacrolimus EP Impurity D is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; 8-epi Tacrolimus; 8-Epitacrolimus; Tacrolimus anhydrous 8-epimer; Tacrolimus 8-epimer [USP-RS]; Tacrolimus monohydrate impurity D [EP]; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8R*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-; (-)-8-epi-Tacrolimus; (3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Allyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-{(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: ≥90% by HPLC. CAS No. 129212-35-7. Molecular formula: C44H69NO12. Mole weight: 804.04. | |
| Tacrolimus EP Impurity H | Tacrolimus EP Impurity H is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (1E,3S,4R,5S,8R,9E,12S,14S)-5-hydroxy-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-14-methoxy-14-[(2R,3S,5R)-3-methoxy-5-methyl-6-oxooxan-2-yl]-2,4,10,12-tetramethyl-7-oxo-8-(prop-2-en-1-yl)tetradeca-1,9-dien-3-yl (2S)-1-formylpiperidine-2-carboxylate; Tacrolimus monohydrate impurity H [EP]; 2-Piperidinecarboxylic acid, 1-formyl-, (1S,2R,3S,6R,7E,10S,12S)-3-hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-12-methoxy-2,8,10-trimethyl-5-oxo-6-(2-propen-1-yl)-12-[(2R,3S,5R)-tetrahydro-3-methoxy-5-methyl-6-oxo-2H-pyran-2-yl]-7-dodecen-1-yl ester, (2S)-; (1S,2R,3S,6R,7E,10S,12S)-3-Hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-12-methoxy-2,8,10-trimethyl-5-oxo-6-(2-propen-1-yl)-12-[(2R,3S,5R)-tetrahydro-3-methoxy-5-methyl-6-oxo-2H-pyran-2-yl]-7-dodecen-1-yl (2S)-1-formyl-2-piperidinecarboxylate; 2-Piperidinecarboxylic acid, 1-formyl-, (1S,2R,3S,6R,7E,10S,12S)-3-hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-12-methoxy-2,8,10-trim. Grades: ≥95%. CAS No. 143210-33-7. Molecular formula: C43H69NO11. Mole weight: 776.01. | |
| Tacrolimus EP Impurity I | Tacrolimus EP Impurity I is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5E, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-19-hydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; Tacrolimus diene; 23,24-Anhydro Tacrolimus; Δ23-FK-506; Tacrolimus Impurity I; Tacrolimus monohydrate impurity I [EP]; 15,19-Epoxy(5E,9E)-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-tetradecahydro-19-hydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propen-1-yl)-, (3S, 4R, 8R, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-tetradecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5E, 8S*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-. Grades: ≥90% by HPLC. CAS No. 104987-16-8. Molecular formula: C44H67NO11. Mole weight: 786.02. | |
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