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| Product | Description | |
|---|---|---|
| Tafamidis | Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. It is a drug for the amelioration of transthyretin-related hereditary amyloidosis. It functions by kinetic stabilization of the correctly folded tetrameric form of the transthyretin (TTR) protein and binds selectively and with negative cooperativity to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR. Synonyms: Fx-1006A; Vyndaqel. Grades: >98%. CAS No. 594839-88-0. Molecular formula: C14H7Cl2NO3. Mole weight: 308.12. |  |
| Tafamidis | Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 594839-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852. |  |
| Tafamidis meglumine | Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fx-1006A. CAS No. 951395-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852A. | |
| 2-(3,5-Dichlorophenyl)-6-benzoxazolecarboxylic acid | 2-(3,5-Dichlorophenyl)-6-benzoxazolecarboxylic acid. Group: Biochemicals. Alternative Names: Tafamidis; Fx 1006. Grades: Highly Purified. CAS No. 594839-88-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C14H7Cl2NO3. US Biological Life Sciences. |  Worldwide |
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