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Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn 2+ - mTOR pathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFP-168; MK2452. CAS No. 209860-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0600.
Tafluprost
Tafluprost. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylmethyl Ester; AFP 168; MK 2452; Taflotan; Tapros. Grades: Highly Purified. CAS No. 209860-87-7. Pack Sizes: 2.5mg. Molecular Formula: C25H34F2O5, Molecular Weight: 452.53. US Biological Life Sciences.
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Tafluprost
Tafluprost is a novel prostanoid analogue that activates Prostaglandin Receptor. It is used in the treatment of glaucoma and is the first prostanoid to be released in a preservative free-formula. Synonyms: AFP-168, AFP-168, AFP-168, MK-2452, MK2452, MK 2452, Taflotan; Zioptan; AFP-168; Saflutan; propan-2-yl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate. Grades: ≥ 98%. CAS No. 209860-87-7. Molecular formula: C25H34F2O5. Mole weight: 452.539.
Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with K i and EC 50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor ( IC 50 =67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFP-172. CAS No. 209860-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0601.
Tafluprost ethyl ester is an analog of prostaglandin F2α (PGF2α), which has been approved for the treatment of glaucoma. Synonyms: AFP 175; Ethyl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate. Grades: ≥98%. CAS No. 209860-89-9. Molecular formula: C24H32F2O5. Mole weight: 438.5.
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