Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Talabostat mesylate | Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. Uses: For research used only. Synonyms: (R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-ylboronic acid methanesulfonic acid (1:1); PT-100; PT100; PT 100; D05989; D-05989; D 05989; Val-boro-pro; Talabostat. Grades: 98%. CAS No. 150080-09-4. Molecular formula: C10H23BN2O6S. Mole weight: 310.17. |  |
| Talabostat mesylate | Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor ( IC 50 < 4 nM; K i = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) ( IC 50 = 560 nM), inhibits DPP8/9 ( IC 50 = 4/11 nM; K i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) ( IC 50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Val-boroPro mesylate; PT100 mesylate. CAS No. 150080-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13233A. |  |
Our database is helping our users find suppliers everyday.
