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Talaporfin sodium Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ME2906; Mono-L-aspartyl chlorin e6; NPe6. CAS No. 220201-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16477. MedChemExpress MCE
Talaporfin sodium Talaporfin sodium is a natural chlorophyll-based, and water soluble PDT photosensitizer consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity. After intratumoral activation by light emitting diodes, talaporfin sodium forms an extended high energy conformational state that generates singlet oxygen, which can kill target tissues with minimal side effects through vascular closure and apoptosis. Constant illumination can activate each molecule of talaporfin many times, resulting in a continuous supply of singlet oxygen molecules. Talaporfin kills all tumour cells in the targeted zone, rather than only the minority of cells undergoing rapid division, as in the case of chemotherapy. There are no serious toxicities to date. Talaporfin sodium was approved in 2004 in Japan, and is currently in phase III trials in USA. Synonyms: LS11, LS-11, LS 11, ME2906, ME 2906, ME-2906, NPe6; mono-L-aspartyl chlorin e6; Laserphyrin; Mono-L-aspartyl chlorin e6; LS-11; ME-2906. Grades: >98%. CAS No. 220201-34-3. Molecular formula: C38H37N5Na4O9. Mole weight: 799.69. BOC Sciences 9

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