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| Product | Description | |
|---|---|---|
| Tamibarotene | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Tamibarotene | Synthetic retinoic acid receptor-α/ β-selective retinoid. Antineoplastic. Group: Biochemicals. Alternative Names: 4-[[ (5, 6, 7, 8-Tetrahydro-5, 5, 8, 8-tetramethyl-2-naphthalenyl) amino]carbonyl]benzoic Acid. Grades: Highly Purified. CAS No. 94497-51-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Tamibarotene | Tamibarotene. CAS No. 94497-51-5. Product ID: 8-04574. Molecular formula: C22H25NO3. Mole weight: 351.45. Purity: 0.99. |  |
| Tamibarotene | Tamibarotene is an orally active retinoic acid receptor α (RARα) agonist, showing high selectivity over RAR&gamma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Am 80. CAS No. 94497-51-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14652. |  |
| Tamibarotene | Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation and apoptosis of HL-60 cells in vitro. It exhibits antiproliferative effects against a variety of human tumor cells lines and displays anticancer activity against acute promyelocytic leukemia in vivo. It is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. It may show sustained plasma levels compared to ATRA. It may exhibit a lower toxicity profile than ATRA, in part, due to the lack of affinity for the RAR-gamma receptor, the major retinoic acid receptor in the dermal epithelium. Synonyms: Retinobenzoic acid; Amnoid; AMNOLAKE; Am80; Am 80; Am-80; SY-1425; SY 1425; SY1425; Tamibarotene. Grades: 98%. CAS No. 94497-51-5. Molecular formula: C22H25NO3. Mole weight: 351.44. |  |
| Keto tamibarotene | Keto tamibarotene. Group: Biochemicals. Alternative Names: 4-[[ (5, 6, 7, 8-Tetrahydro-5, 5, 8, 8-tetramethyl-6-oxo-2-naphthalenyl) amino]carbonyl]. Grades: Highly Purified. CAS No. 162661-91-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H23NO4. US Biological Life Sciences. | Worldwide |
| K145 | K145 is a selective sphingosine kinase-2 (SphK2) inhibitor and anticancer agent. K145 inhibited the activity of SphK2 in a dose-dependent manner with an IC50 of 4.30±0.06 μM. K145 also exhibited inhibitory effects on the growth of U937 cells as well as apoptotic effects in U937 cells. K145 exhibits comparable in vivo anti-tumor activity to tamibarotene, while concomitantly exhibiting less toxicity in this U937 xenograft cancer model. Synonyms: SphK2 inhibitor; K 145; K-145. Grades: >98%. CAS No. 1309444-75-4. Molecular formula: C18H24N2O3S. Mole weight: 348.46. | |
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