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| Product | Description | |
|---|---|---|
| TAS-103 | TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be a potent topoisomerase II poison. TAS-103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0.05). The combination with CDDP augmented the antitumor activity of TAS-103 (p<0.05), indicating that CDDP is one of the most potent candidates to be used in combination with TAS-103. TAS-103 may be useful in the chemotherapy of colorectal cancer. Uses: Topoisomerase i inhibitors. Synonyms: BMS-247615; TAS103; TAS 103; BMS247615; BMS 247615. Grades:>98%. CAS No. 174634-08-3. Molecular formula: C20H19N3O2. Mole weight: 333.38. |  |
| TAS-103 dihydrochloride | TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models. TAS-103 has been reported to be a potent topoisomerase II poison. TAS-103 showed the strongest antitumor activity among the conventional anticancer agents for colorectal cancer (p<0.05). The combination with CDDP augmented the antitumor activity of TAS-103 (p<0.05), indicating that CDDP is one of the most potent candidates to be used in combination with TAS-103. Synonyms: 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride; TAS103; TAS-103; TAS 103; BMS247615; BMS 247615; BMS-247615. Grades:>98%. CAS No. 174634-09-4. Molecular formula: C20H21Cl2N3O2. Mole weight: 406.31. | |
| TAS-301 | TAS-301 is a potent and selective constrictive remodeling regulator on renarrowing after balloon overstretch injury of porcine coronary artery. TAS-103 inhibits smooth muscle cell migration and proliferation. Synonyms: TAS-301; TAS301; TAS301. Grades: 98%. CAS No. 193620-69-8. Molecular formula: C23H19NO3. Mole weight: 357.41. | |
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