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| Product | Description | |
|---|---|---|
| tBID | tBID is a selective inhibitor of homeodomain-interacting protein kinase 2 ( HIPK2 ) with an IC 50 of ?0.33 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1639895-85-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100464. |  |
| tBID | tBID specificly inhibits homeodomain-interacting protein kinase 2 (HIPK2) (IC50=?0.33 μM). Synonyms: 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl)isoindole-1,3-dione. CAS No. 1639895-85-4. Molecular formula: C11H3Br4N3O2. Mole weight: 528.78. |  |
| BI-6C9 | BI-6C9 ( N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide) is a tBid inhibitor that possesses antiapoptotic properties. Bid plays an essential role in matrine-induced AIF translocation. BI-6C9 also blocked matrine-induced AIF translocation detected by confocal microscopy. Bid inhibitor BI-6C9 was applied to confirm the essential role of Bid in cell death induced by matrine. Synonyms: N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-butanamide. Grades: ≥98%. CAS No. 791835-21-7. Molecular formula: C23H25N3O4S2. Mole weight: 471.6. | |
| MIM1 (4-(E)-[[(2Z)-2-cyclohexylimino)-4-m ethyl-1, 3-thiazol-3 (2H) -yl] imino] methyl] benzene-1, 2,3-triol) | MIM1 (4-(E)-[[(2Z)-2-cyclohexylimino)-4-m ethyl-1, 3-thiazol-3 (2H) -yl] imino] methyl] benzene-1, 2,3-triol). Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C17H21N3O3S, Biological Activity: Inhibitor of Mcl-1; selectively targets the BH3-binding pocket. Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro. US Biological Life Sciences. |  Worldwide |
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