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| Product | Description | |
|---|---|---|
| TC ASK 10 | TC ASK 10. Group: Biochemicals. Grades: Purified. CAS No. 1005775-56-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TC ASK 10 | TC ASK 10 is a potent and orally bioactive ASK1 inhibitor (IC50 = 14 nM) with selectivity for ASK1 over other kinases including ASK2 (IC50 = 0.51 μM), MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf (IC50 > 10 μM). TC ASK 10 blocks downstream JNK1/p38 phosphorylation in cells. Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride; ASK1 Inhibitor 10. Grades: ≥98% by HPLC. CAS No. 1005775-56-3. Molecular formula: C21H21N5O.2HCl. Mole weight: 432.35. |  |
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