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| Product | Description | |
|---|---|---|
| TC-N 1752 | TC-N 1752. Group: Biochemicals. Grades: Purified. CAS No. 1211866-85-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TC-N 1752 | TC-N 1752 is a potent and orally active inhibitor of Nav1.7, with IC50s of 0.17 ?M, 0.3 ?M, 0.4 ?M, 1.1 ?M and 2.2 ?M at hNav1.7, hNav1.3, hNav1.4, hNaV1.5 and rNav1.8, respectively. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. TC-N 1752 shows analgesic efficacy in the Formalin model of pain[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1211866-85-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107405. |  |
| TC-N 1752 | TC-N 1752 is a state-dependent human NaV channel inhibitor (IC50 = 0.17, 0.3, 0.4, 1.1 and 1.6 μM at hNaV1.7, hNaV1.3, hNaV1.4, hNaV1.5 and hNav1.9, respectively). TC-N 1752 inhibits Nav1.7 and exhibits analgesic efficacy in the formalin pain model. TC-N 1752 also inhibits tetrodotoxin-sensitive sodium channels. Synonyms: N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide; Nav1.7 blocker 52. Grades: ≥99% by HPLC. CAS No. 1211866-85-1. Molecular formula: C25H27F3N6O3. Mole weight: 516.52. |  |
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