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| Product | Description | |
|---|---|---|
| TC-S 7009 | TC-S 7009. Group: Biochemicals. Grades: Purified. CAS No. 1422955-31-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TC-S 7009 | TC-S 7009 is a high affinity and selective HIF-2α inhibitor (Kd = 81 nM) that displays >60-fold selectivity for HIF-2α over HIF-1&alpha. TC-S 7009 binds to the HIF-2α PAS-B domain to disrupt HIF-2α-ARNT heterodimerization, decrease HIF-2α DNA-binding and suppress expression of HIF-2α target genes in vitro. Synonyms: TCS 7009; TC S 7009; TC-S 7009; N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine. Grades: ≥99% by HPLC. CAS No. 1422955-31-4. Molecular formula: C12H6ClFN4O3. Mole weight: 308.65. |  |
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