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TCB-2 TCB-2. Group: Biochemicals. Grades: Purified. CAS No. 912342-28-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
TCB-2 TCB-2 is a high affinity 5-HT2A receptor agonist (Ki = 0.73 and 0.75 nM for rat and human receptors, respectively). TCB-2 stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors (EC50 = 36 nM). It also induces head twitches and hypothermia in mice following i.p. adminitration. Synonyms: TCB 2; TCB2; (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide; Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3-bromo-2,5-dimethoxy-, hydrobromide (1:1); Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine, 3-bromo-2,5-dimethoxy-, monohydrobromide; (3-bromo-2,5-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methanamine hydrobromide. Grades: ≥99% by HPLC. CAS No. 912342-28-0. Molecular formula: C11H14BrNO2.HBr. Mole weight: 353.05. BOC Sciences 10

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