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| Product | Description | |
|---|---|---|
| TCS 21311 | TCS 21311. Group: Biochemicals. Grades: Purified. CAS No. 1260181-14-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TCS 21311 | TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM) with selectivity for JAK3 over JAK1, JAK2 and TYK2 (IC50 = 1017, 2550 and 8055 nM, respectively). It also inhibits GSK-3β, PKCα and PKCθ (IC50 = 3, 13 and 68 nM, respectively). Synonyms: NIBR3049; NIBR-3049; NIBR 3049; TCS-21311; TCS 21311; TCS21311; 3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: ≥98% by HPLC. CAS No. 1260181-14-3. Molecular formula: C27H25F3N4O4. Mole weight: 526.51. |  |
| TCS-21311 | A potent JAK3 inhibitor; selective for JAK3 over JAK1, JAK2 and TYK2. It also inhibits GSK-3 β, PKCα and PKC?. Group: Biochemicals. Alternative Names: 3-[5-[4- (2-Hydroxy-2-methyl-1-oxopropyl) -1-piperazinyl]-2- (trifluoromethyl) phenyl]-4- (1H-indol-3-yl) -1H-pyrrole-2, 5-dione; TCS 21311. Grades: Highly Purified. CAS No. 1260181-14-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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