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| Product | Description | |
|---|---|---|
| TCS JNK 6o | TCS JNK 6o. Group: Biochemicals. Grades: Purified. CAS No. 894804-07-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TCS JNK 6o | TCS JNK 6o is an ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor with Kis of 2, 4 and 52 nM for JNK1, JNK2 and JNK3, respectively, and IC50s of 45 and 160 nM for JNK1 and JNK2, respectively. It shows >1000-fold selectivity over other kinases, including ERK2 and p38. It can inhibit apoptosis, caspase cleavage and cytochrome C release. Synonyms: JNK Inhibitor VIII; N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide; Benzeneacetamide, N-(4-amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxy-. Grades: ≥98% by HPLC. CAS No. 894804-07-0. Molecular formula: C18H20N4O4. Mole weight: 356.38. |  |
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