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| Product | Description | |
|---|---|---|
| Tecovirimat | Tecovirimat Inhibitor. Uses: Scientific use. Product Category: T17026. CAS No. 869572-92-9. |  |
| Tecovirimat | Tecovirimat is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of smallpox in adults and children. (Smallpox is a disease caused by the variola virus, a member of the orthopoxvirus group of viruses. Since 1980, smallpox has been considered eradicated worldwide.) Although tecovirimat is only approved for smallpox treatment, it may also be used to treat other types of orthopoxvirus infections, including mpox. Tecovirimat can be used for mpox treatment through an expanded access program (also known as compassionate use) or through clinical trials. Alternative Names: ST-246;SIGA-246. CAS No. 816458-31-8. Product ID: API816458318. Molecular formula: C19H15F3N2O3. Mole weight: 376.3. SMILES: C1C2C1C3C=CC2C4C3C(=O)N(C4=O)NC(=O)C5=CC=C(C=C5)C(F)(F)F. Standard: Facility GMP. Category: Antivirus APIs. |  |
| Tecovirimat | Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC 50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene , which is homologous to vaccinia virus F13L , encoding a major envelope protein (p37) required for production of extracellular virus [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ST-246. CAS No. 869572-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14805. |  |
| Tecovirimat monohydrate | Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC 50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene , which is homologous to vaccinia virus F13L , encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ST-246 monohydrate. CAS No. 1162664-19-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14805A. | |
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