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| Product | Description | |
|---|---|---|
| Temsirolimus | Temsirolimus is an inhibitor of mTOR with an IC 50 of 1.76 μM. Temsirolimus activates autophagy and prevents deterioration of cardiac function in animal model [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCI-779. CAS No. 162635-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50910. |  |
| Temsirolimus Acetonide | Rapamycin 42-ester derivative. Group: Biochemicals. Alternative Names: Rapamycin 42-(2,2,5-Trimethyl-1,3-dioxane-5-carboxylate). Grades: Highly Purified. CAS No. 162635-03-2. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Temsirolimus-d3 | Labeled ester analog of Rapamycin. Group: Biochemicals. Alternative Names: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-(methyl-d3)-propanoate; CCL-779-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Temsirolimus-d7 | Labelled ester analog of Rapamycin. Group: Biochemicals. Alternative Names: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate-d7; CCL-779-d7. Grades: Highly Purified. CAS No. 1132660-51-5. Pack Sizes: 1mg. Molecular Formula: C56H80D7NO16, Molecular Weight: 1037.33. US Biological Life Sciences. | Worldwide |
| Temsirolimus Impurity 1 | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: 7-O-Desmethyl Temsirolimus; (7ξ)-7-O-Demethyl-rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]. Grades: > 95%. CAS No. 408321-08-4. Molecular formula: C55H85NO16. Mole weight: 1016.29. |  |
| Temsirolimus Impurity 2 | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: Temsirolimus Isomer C. Grades: > 95%. CAS No. 1027067-40-8. Molecular formula: C56H87NO16. Mole weight: 1030.31. | |
| Temsirolimus isomer C | Temsirolimus isomer C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 150821-39-9. Molecular Formula: C51H79NO13. Mole Weight: 914.17. Catalog: APB150821399. |  |
| Temsirolimus (Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate, CCL-779) | Ester analog of rapamycin. Group: Biochemicals. Alternative Names: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate; CCL-779. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 12-ethyl-Temsirolimus | 12-ethyl-Temsirolimus. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 12-ethyl-Temsirolimus. Molecular Formula: C52H81NO13. Mole Weight: 928.2. Catalog: APB01977. | |
| Pipendoxifene | Pipendoxifene, also known as ERA-923, is a new antiestrogen with potential anticancer activity. ERA-923 potently inhibits estrogen binding to ER-alpha (IC50=14 nM). In ER-alpha-positive human MCF-7 breast carcinoma cells, ERA-923 inhibits estrogen-stimulated growth (IC50=0.2 nM) associated with cytostasis. In vitro, a MCF-7 variant with inherent resistance to tamoxifen (10-fold) or 4-OH tamoxifen (>1000-fold) retains complete sensitivity to ERA-923. In preclinical models, ERA-923 has an improved efficacy and safety compared with tamoxifen. In the combination with temsirolimus, ERA-923 showed excellent anticancer activity in preclinical models. Synonyms: ERA-923; ERA 923; ERA923; 2-(p-Hydroxyphenyl)-3-methyl-1-(p-(2-piperidinoethoxy)benzyl)indol-5-ol. Grades: >98%. CAS No. 198480-55-6. Molecular formula: C29H32N2O3. Mole weight: 456.58. | |
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