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| Product | Description | |
|---|---|---|
| Tenovin-1 | Tenovin-1, a p53 activator, protects p53 from MDM2-mediated degradation. Tenovin-1 acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also a dihydroorotate dehydrogenase (DHODH) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 380315-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13423. |  |
| Tenovin-1 | Tenovin-1. Group: Biochemicals. Grades: Purified. CAS No. 380315-80-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Tenovin-1 - CAS 380315-80-0 | A cell-permeable benzoylthiourea compound that acts as a reversible inhibitor of class III HDAC sirtuins against SirT2 (IC?? = ~ 10 μM). Group: Fluorescence/luminescence spectroscopy. |  |
| Tenovin-6 | Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC 50 s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1011557-82-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15510. | |
| Tenovin-6 Hydrochloride | Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC 50 s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1011301-29-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15510B. | |
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